Concerns remain about the acute and chronic effects on personnel of waste anesthetic gases in the operating room environment. This study demonstrates a simple and effective means of scavenging waste anesthetic gases when halogenated anesthetics are administered through the pump oxygenator during cardiopulmonary bypass. This technique safeguards workers' health by reducing ambient anesthetic lev...

background: the aim of this study was assessment the risk management status of waste anesthetic gases in academicals hospitals in iran to prevent from harmful effects of these gases on employees' health. methods: a descriptive-analytic study was designed in 2011. standard structured checklist developed by ecri institute (emergency care research institute) was applied. checklists were filled ons...

Pauling and Miller have independently proposed that the presence of an anesthetic gas in tissue induces a cage-like arrangement of hydrogen-bonded water molecules. The theories recognize that most gas-hydrate crystals would not form at the temperature and pressure that exist during anesthesia and propose that other components of tissue such as protein should have a stabilizing effect. Measureme...

Noble gases seem to have no significant effect on the anesthetic targets due to their simple, spherical shape. However, xenon has strong narcotic efficacy and can be used clinically, while other noble gases cannot. The mechanism remains unclear. Here, we performed molecular dynamics simulations on phospholipid bilayers with four kinds of noble gases to elucidate the difference of their effects ...

Background: Although eliminated rapidly from the body due to low solubility in blood and tissues, anesthetic gases have been reported to be neurotoxic, teratogenic and carcinogenic. Genetic material has been shown to be a sensitive target of numerous harmful agents. Aim of the Work: To evaluate genotoxic risk of occupational exposure to anesthetic gases in a group of operating room nurses. Subj...

BACKGROUND The administration of anesthetics determines depression of the central nervous system and general anesthesia by inhalation may cause an environmental pollution of the operating rooms. It may therefore conceive a possible occupational etiology of Parkinson's Disease (PD). CASE PRESENTATION In a Caucasian male aged 59 years, PD was diagnosed by brain scans with a presynaptic radioact...

Nitrous oxide, xenon, and cyclopropane are anesthetic gases that have a distinct pharmacological profile. Whereas the molecular basis for their anesthetic actions remains unclear, they behave very differently to most other general anesthetics in that they have little or no effect on GABAA receptors, yet strongly inhibit the N-methyl-d-aspartate subtype of glutamate receptors. Here we show that ...