BACKGROUND Amitraz, an insecticide used to prevent tick and mite infestation of cattle, crops and dogs, is an alpha2-adrenergic receptor agonist that inhibits GnRH release and the ovulatory LH surge in rats. Noradrenalin, the physiological ligand for adrenergic receptors, inhibits progesterone production by IVF-derived granulosa cells, but the effects of amitraz are unknown. METHODS Luteinize...

Experimental amitraz intoxication and its reversal by atipamezole and yohimbine were studied in cats. Twenty four cats were randomly divided equally into 3 groups: Group A (amitraz); Group AY (amitraz/yohimbine) and Group AA (amitraz/atipamezole). Sedation, loss of reflexes, hypothermia, bradycardia, bradyarrhythmia, hypotension, bradypnea, mydriasis, and initial transitory hyperglycemia occurr...

AIMS OF THE STUDY To report the clinical features, laboratory findings and the management instituted for the patients with acute Amitraz Poisoning. METHODS AND MATERIAL Three cases of acute Amitraz Intoxication were studied and compared with previous reports from the literature. RESULTS All the three female cases were brought to our hospital with age ranging from 2 years to 40 years, consum...

Amitraz is commonly used in agricultural industries throughout the world as a farm-animal insecticide. Despite its widespread use, amitraz intoxication is extremely rare and mainly occurs through accidental ingestion by young children. Severe, life-threatening amitraz intoxication in adults is very rarely recognized and reported. Described herein is a previously healthy 54-year-old patient who ...

Amitraz is a formamidine compound used in veterinary medicine as a topical dip to control ticks and mites on dogs and livestock. A 10-year-old female Scottish terrier was presented following the accidental oral administration of a dip containing amitraz. This case report describes the clinical signs, treatment and pathology of this dog. Clinical signs of toxicity from amitraz result from stimul...

INTRODUCTION Analysis of the annual pesticide poisoning statistics of the Tygerberg Poison Information Centre (TPIC) for the period 2005-2007 showed an increase in the number of amitraz poisonings. This prompted a 2-year survey (2008-2009) to establish the extent of amitraz poisoning in South Africa. Amitraz is a pesticide used as a tick dip. It acts as an α(2)-adrenoceptor agonist and the prin...

Acaricide resistance is a major problem that hinders the control of the tropical cattle tick, Rhipicephalus (Boophilus) microplus (Canestrini), in many parts of the world where cattle production continues to suffer severe economic losses to tick infestation. Deltamethrin and amitraz have been used alone to control R. microplus in New Caledonia for the past decade, and tick populations have deve...

Background: To determine the atmospheric contamination by pesticides, conducting laboratory studies is necessary before operating field studies. The aim of this research study was to develop an analytical method to sample and simultaneously determine airborne amitraz and its metabolite. Methods: A modified fritted impinger with acetonitrile as the liquid sorbent was used in order to study the a...

BACKGROUND & OBJECTIVES Amitraz is a member of formamidine family of pesticides. Poisoning from amitraz is underrecognized even in areas where it is widely available. It is frequently misdiagnosed as organophosphate poisoning. This systematic review provides information on the epidemiology, toxicokinetics, mechanisms of toxicity, clinical features, diagnosis and management of amitraz poisoning....

Amitraz, a formamidine acaricide, plays an important role in the control of the southern cattle tick, Boophilus microplus (Canestrini), and other tick species that infest cattle, dogs, and wild animals. Although resistance to amitraz in B. microplus was previously reported in several countries, the actual measurement of the level of amitraz resistance in ticks has been difÞcult to determine due...