Ameloblastomas and adenomatoid odontogenic tumors (AOTs) are common epithelial tumors of odontogenic origin. Ameloblastomas are clinico-pathologically classified into solid/multicystic, unicystic, desmoplastic, and peripheral types, and also divided into follicular, plexiform, acanthomatous, granular types, etc., based on their histological features. Craniopharyngiomas, derived from the remnant...

UNLABELLED BACKGROUND An ameloblastoma is a benign odontogenic neoplasm with aggressive behaviour and high recurrence rates. The increased expression of matrix metalloproteinases (MMPs) has been reported in ameloblastomas. In the present study, we hypothesised that epigenetic alterations may regulate MMP expression in ameloblastomas. METHODS We investigated the methylation status of the ge...

UNLABELLED Recently, the World Health Organization (WHO) excluded the desmoplastic pattern from the histopathological spectrum of solid ameloblastomas and classified it as a distinct variant, named desmoplastic ameloblastoma. AIM To perform a retrospective analysis of the clinicopathologic aspects in a case series of solid ameloblastomas. STUDY DESIGN Cross-sectional cohort study. MATERIA...

Introduction: Ameloblastoma is an odontogenic tumour with high recurrence rate. The objective of the present study was to evaluate existing literature regarding clinical, radiographic, histopathologic features, treatment, and rate ameloblastomas compare it features recurrent ameloblastomas. Materials methods: A systematic review done based on PRISMA statement. Search performed in “Pubmed” datab...

.. Objectives: The aim of study was to observe the expression of MCM2 in dentigerous cyst and ameloblastoma. Introduction: Minichromosome maintenance protein (MCM2) may be a structurally and functionally complicated replication moiety that synergizes with different molecular factors therefore regulate DNA synthesis. MCM proteins play a job in maintaining genomic integrity and stop re-replicatio...

UNLABELLED Ameloblastomas are odontogenic tumors that can present some distinct clinicopathological profiles when comparing different populations and studies. OBJECTIVES The aim of the present study was to analyze the clinicopathological features from a series of ameloblastomas diagnosed in a single Oral Pathology service in Brazil in an 8-year period. STUDY DESIGN The files were revised an...

BACKGROUND Ameloblastomas and keratocystic odontogenic tumors (KOTs) are lesions that are characterized by locally invasive growth and cause extensive bone destruction. In addition, it is known that E-cadherin influences the adhesion of Langerhans cells (LCs) to keratinocytes. OBJECTIVE AND METHODS The aim of this study was to investigate, using immunohistochemistry, the distribution of CD1a-...

OBJECTIVES The aim of this study was to compare among PCNAand Ki-67 as the most reliable immunohistochemical marker for evaluating cell proliferation in ameloblastic tumors. STUDY DESIGN Observational, retrospective, and descriptive study of a large series of ameloblastic tumors, composed of 161 ameloblastomas and four ameloblastic carcinomas, to determine and compare PCNA and Ki-67 expressio...

Multicystic and unicystic ameloblastomas are benign odontogenic tumors that present distinct biological behavior. The investigation of stem cells has become an important branch of tumor biology, with several studies addressing the possible role of these cells in tumor growth, angiogenesis, progression, infiltration and invasiveness. This study evaluated the immunohistochemical expression of CD9...

BACKGROUND & OBJECTIVE Matrix metalloproteinases (MMPs) are involved in local invasion of ameloblastomas. This study was to evaluate the role of matrix metalloproteinase inducer (EMMPRIN) in angiogenesis in ameloblastomas by analyzing EMMPRIN expression and microvessel density (MVD) in ameloblastomas and odontogenic cysts. METHODS EMMPRIN expression and MVD in 41 specimens of ameloblastoma an...