OBJECTIVES The aim of this study was to compare among PCNAand Ki-67 as the most reliable immunohistochemical marker for evaluating cell proliferation in ameloblastic tumors. STUDY DESIGN Observational, retrospective, and descriptive study of a large series of ameloblastic tumors, composed of 161 ameloblastomas and four ameloblastic carcinomas, to determine and compare PCNA and Ki-67 expressio...

Spindle-cell differentiation in ameloblastic carcinoma is a rare event. Although reported by many authors, it was first described as a separate entity in 1999 by Slater under the heading "low-grade spindle-cell ameloblastic carcinoma." Here, we report a case of low-grade spindle-cell ameloblastic carcinoma arising in pre-existing unicystic ameloblastoma.The patient, a 60-year-old Indian woman, ...

AIM To evaluate the use of proliferating cell nuclear antigen index in the different histopathological variants of ameloblastoma, such as the follicular, plexiform, and unicystic types, and in ameloblastic carcinoma by immunohistochemical staining. The proliferating cell nuclear antigen index values of the variants of ameloblastomas and ameloblastic carcinomas are compared in order to determine...

Ameloblastic fibroma (AF) is an uncommon benign odontogenic tumour, with both epithelial and mesenchymal neoplastic proliferation. It occurs most frequently in the posterior region of the mandible, while its occurrence in the maxilla is extremely rare. They are usually encountered in children, emphasizing it as an important diagnostic consideration. Herein, we report the first case of a bilater...

Protein delta homolog 1 (DLK1) regulates the odontoblastic differentiation of human dental pulp stem cells. It was hypothesized that DLK1 may exert regulatory effects on epithelial‑mesenchymal interactions in tooth development. The present study investigated the expression of DLK1 during the development of mouse enamel and its role in the proliferation and differentiation of ameloblast‑lineage ...

INTRODUCTION Ameloblastic fibro-odontoma is a rare, benign, asymptomatic tumor. The term ameloblastic fibro-odontoma was first used by Hooker in 1967 as a separate lesion from ameloblastic odontoma. CASE REPORT This case report describes an eleven years old female with large ameloblastic fibro-odontoma in the right maxillary sinus. CONCLUSION There is a low potential for recurrence after co...

INTRODUCTION Ameloblastic fibroma (AF) is a rare benign odontogenic tumor that usually occurs in the fi two decades of life. It affects adolescents and young adults and is found in the mandible and with a high frequency in the posterior region of this segment. There are rare case reports with a long-term follow-up. CASE OUTLINE We report the case of a 6-year-old boy with extensive ameloblasti...

Abstract Ameloblastic fibroma is a relatively rare benign odontogenic tumor with two neoplastic components both epithelial and ectomesenchymal. A 10-year-old girl was referred to a dentist for routine dental treatments for evaluation of the distance between mandibular right first permanent molar and mandibular right second deciduous molar and it was associated with an undesirable backward mov...

Calcifying odontogenic cyst is a developmental odontogenic cyst first described by Gorlin in 1962. It is considered as an extremely rare condition and shows extensive diversity in its clinicopathological appearances and biologic behavior. In this report a rare case of calcifying odontogenic cyst with ameloblastic proliferation (an extremely rare histologic variant) with one year follow – up is ...

Ameloblastic fibro-odontoma (AFO) is a rare benign mixed odontogenic tumor. It is a slow-growing generally asymptomatic lesion and more prevalent in children and adolescents. This article presents interesting case of ameloblastic fibro-odontoma involving anterior maxilla of 15-year-old male patient. Occlusal radiograph showed a large, well-demarcated radiolucency with radiopaque areas and minia...