نتایج جستجو برای: Alpha-tocotrienol

تعداد نتایج: 202822  

Journal: :The Journal of nutrition 2009
Harumi Uto-Kondo Reiko Ohmori Chikako Kiyose Yoshimi Kishimoto Hisako Saito Osamu Igarashi Kazuo Kondo

In vivo studies show that alpha-tocotrienol and gamma-tocotrienol accumulate in adipose tissue. Furthermore, a recent study reports that the oral administration of gamma-tocotrienol from a tocotrienol-rich fraction from palm oil (TRF) decreases body fat levels in rats. The objective of this study was to evaluate the effect of TRF and its components on adipocyte differentiation in 3T3-L1 preadip...

Journal: :Asia Pacific journal of clinical nutrition 2005
Paul W Sylvester Sumit Shah

Tocotrienols and tocopherols represent the two subgroups that make up the vitamin E family of compounds. However, tocotrienols display significantly more potent apoptotic activity in neoplastic mammary epithelial cells than tocopherols. Studies were conducted to determine the intracellular mechanism(s) mediating tocotrienol-induced apoptosis in neoplastic +SA mouse mammary epithelial cells in v...

Journal: :Sains Malaysiana 2021

Tocotrienol mixtures have been shown to exert anabolic actions on the skeletal system in animal studies, but it is unclear which tocotrienol isomer shows most prominent effects. This study aims investigate active isomers using hFOB 1.19 human osteoblasts cultured a bovine bone scaffold. The trabecular was sectioned, demineralised and freeze-dried form were scaffolds humidified condition at 37 °...

Journal: :Current pharmaceutical design 2011
Jayeeta Bardhan Runu Chakraborty Utpal Raychaudhuri

Vitamin E family constitutes of tocopherol and tocotrienol. Each form has several isomers: alpha,beta, gamma, delta, desmo and didesmo. Although tocopherol is known much earlier, tocotrienol has been discovered more recently.Tocotrienol has higher antioxidant potential than tocopherol. Research shows that tocotrienol can inhibit the induced oxidative damage to lipids and proteins. Cholesterol b...

Journal: :Free radical biology & medicine 2003
Jürgen Fuchs Stefan Weber Maurizio Podda Norbert Groth Thomas Herrling Lester Packer Roland Kaufmann

The content and composition of different vitamin E isoforms was analyzed in normal human skin. Interestingly the epidermis contained 1% alpha-tocotrienol, 3% gamma-tocotrienol, 87% alpha-tocopherol, and 9% gamma-tocopherol. Although the levels of tocotrienol in human epidermis appear to be considerably lower than reported in the hairless mouse, the presence of significant amounts of tocotrienol...

Journal: :iranian journal of basic medical sciences 0
mohammad allahtavakoli department of physiology, school of medicine, rafsanjan university of medical sciences, rafsanjan, iran aliasghar pourshanazari department of physiology, school of medicine, rafsanjan university of medical sciences, rafsanjan, iran behnam heshmatian department of physiology, school of medicine, west azarbaeejan university of medical sciences, oroomiah, iran

objective(s) previous studies have demonstrated that pretreatment with alpha-tocotrienol (a-tct) can reduce ischemic damage in mice following middle cerebral artery (mca) occlusion. it is also reported to decrease stroke- dependent brain tissue damage in 12-lox-deficient mice and spontaneously hypertensive rats. in the present study, the neuroprotective effects of a-tct and rosiglitazone (rgz) ...

Journal: :The Journal of nutrition 2007
Chisato Abe Saiko Ikeda Tomono Uchida Kanae Yamashita Tomio Ichikawa

The aim of this experiment was to clarify the contribution of the alpha-tocopherol transfer activity of lipoprotein lipase (LPL) to vitamin E transport to tissues in vivo. We studied the effect of Triton WR1339, which prevents the catabolism of triacylglycerol-rich lipoproteins by LPL on vitamin E distribution in rats. Vitamin E-deficient rats fed a vitamin E-free diet for 4 wk were injected wi...

2012
Norliza Muhammad Douglas Alwyn Luke Ahmad Nazrun Shuid Norazlina Mohamed Ima-Nirwana Soelaiman

Postmenopausal osteoporotic bone loss occurs mainly due to cessation of ovarian function, a condition associated with increased free radicals. Vitamin E, a lipid-soluble vitamin, is a potent antioxidant which can scavenge free radicals in the body. In this study, we investigated the effects of alpha-tocopherol and pure tocotrienol on bone microarchitecture and cellular parameters in ovariectomi...

Journal: :American journal of physiology. Heart and circulatory physiology 2008
Samarjit Das Istvan Lekli Manika Das Gergo Szabo Judit Varadi Bela Juhasz Istvan Bak Kalanithi Nesaretam Arpad Tosaki Saul R Powell Dipak K Das

A recent study from our laboratory indicated the cardioprotective ability of the tocotrienol-rich fraction (TRF) from red palm oil. The present study compared cardioprotective abilities of different isomers of tocotrienol against TRF as recently tocotrienol has been found to function as a potent neuroprotective agent against stroke. Rats were randomly assigned to one of the following groups: an...

Journal: :Journal of the American College of Nutrition 2010
Chandan K Sen Cameron Rink Savita Khanna

A growing body of research supports that members of the vitamin E family are not redundant with respect to their biological function. Palm oil derived from Elaeis guineensis represents the richest source of the lesser characterized vitamin E, alpha-tocotrienol. One of 8 naturally occurring and chemically distinct vitamin E analogs, alpha-tocotrienol possesses unique biological activity that is ...

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