BackgroundThe aim of this study was to evaluate the lipid abnormalities associated with different stages of albuminuria and also examine role of ApoB lipoprotein as a predictor of early diabetic nephropathy in type 2 diabetic patients. Methods and ResultsA total 259 diabetic patients (110 men and 149 women) with mean age group 62.5±11.2 years were studied. Normoalbuminurea (n=110), microalbumin...

objective: the aim of the present study was to investigate the renal protective effect of adenanthera pavonina (a. pavonina) seed aqueous extract (apsae), in streptozotocin (stz)-induced diabetic rats. materials and methods: the renal protective effect of a. pavonina seed aqueous extract (apsae) was studied in stz-induced diabetic rats. apsae (50, 100 and 200 mg/kg per day) was given daily to d...

BackgroundThe aim of this study was to evaluate the lipid abnormalities associated with different stages of albuminuria and also examine role of ApoB lipoprotein as a predictor of early diabetic nephropathy in type 2 diabetic patients. Methods and ResultsA total 100 diabetic patients (58 men and 42 women) with mean age group 59.15±10.4 years were studied. Normoalbuminurea (n=36), microalbuminur...

AIM The present investigates deals with the change in the pharmacokinetic of Sildenafil citrate (SIL) in disease condition like diabetic nephropathy (DN). METHOD Diabetes was induced in rats by administering Streptozotocin i.e. STZ (60 mg/kg, IP) saline solution. Assessment of diabetes was done by GOD-POD method and conformation of DN was done by assessing the level of Creatinine, Blood Urea ...

BACKGROUND Residents of rural communities are often more socially connected compared to urban dwellers. Using family and community support to motivate health behavior change may be useful in rural settings. The objective of this study was to pilot a salt reduction (SR) intervention for rural albuminuria patients using support from family and neighborhood residents compared to a usual care condi...

The concept that oxidative stress contributes to the development of human preeclampsia has never been tested in genetically-defined animal models. Homozygous deletion of catechol-O-methyl transferase (Comt-/-) in pregnant mice leads to human preeclampsia-like symptoms (high blood pressure, albuminurea and preterm birth) resulting from extensive vasculo-endothelial pathology, primarily at the ut...

The efficacy of Ferulsinaic acid (FA) to modulate the antioxidant enzymes and to reduce oxidative stress induced-diabetic nephropathy (DN) was studied. Rats were fed diets enriched with sucrose (50%, wt/wt), lard (30%, wt/wt), and cholesterol (2.5%, wt/wt) for 8 weeks to induce insulin resistance. After a DN model was induced by streptozotocin; 5, 50 and 500 mg/kg of FA were administrated by or...

OBJECTIVE To find the associations between diabetic retinopathy and age at diagnosis, C-peptide level and thyroid-stimulating hormone (TSH) level in Chinese type 2 diabetes mellitus. METHODS 3100 hospitalized type 2 diabetic patients in Peking University People's Hospital were included in this retrospective study. Their medical history and the laboratory data were collected. All the patients ...