The bursa of Fabricius is critical for B cell development and differentiation in chick embryos. This study describes the production in vitro, from dissociated cell suspensions, of cellular agglomerates with functional similarities to the chicken bursa. Co-cultivation of epithelial and lymphoid cells obtained from embryos at the appropriate developmental stage regularly led to agglomerate format...

Purpose: To prepare and evaluate spherical agglomerates of pioglitazone hydrochloride (PGH) for direct compression with different additives. Method: Spherical agglomerates of pioglitazone hydrochloride were prepared by emulsion solvent diffusion method with and without additives (polyethylene glycol 6000, polyvinyl pyrrolidone, β cyclodextrin, Eudragit RS100, low acyl gellan gum and xanthan gum...

The aim of this study was to prepare Spherical agglomerates of Carbamazepine by Quesi-Emulsion Solvent Diffusion system (QESDS) with Ethanol-Chloroform-Water system. Granules were prepared by wet granulation method with different excipients.The prepared agglomerates were evaluated for flowability, compressibility, wettability, packability and solubility. Tablets were prepared and evaluated for ...

Spatiallyand component-resolved kinetic measurements and resulting phase diagrams for CO oxidation on a model catalyst consisting of Pd powder agglomerates supported by a polycrystalline Pt foil are reported. The kinetic data for the micrometer-sized Pt(100) and Pt(110) domains and for the different Pd powder agglomerates of similar dimensions were obtained by local analysis of PEEM video-seque...

a r t i c l e i n f o Keywords: Loose agglomerates Breakage Discrete element method Fine particles This paper presents a numerical study of the breakage of loose agglomerates based on the discrete element method. Agglomerates of fine mannitol particles were impacted with a target wall at different velocities and angles. It was observed that the agglomerates on impact experienced large plastic d...

PURPOSE Agglomeration in suspension is a size enlargement method that facilitates operation of solid processing and preserves the solubilization properties of fine particles. A small quantity of binder liquid is added into a suspension of microparticles, directly in the stirred vessel where the precipitation or crystallization took place. This study deals with the evaluation of the effect of ag...

We propose a porosimetry-based method to characterize pores formed by carbon nanotubes (CNTs) in the CNT agglomerates for designing neat CNT-based materials and composites. CNT agglomerates contain pores between individual CNTs and/or CNT bundles (micropore < 2 nm, mesopores 2-50 nm, and macropores > 50 nm). We investigated these pores structured by CNTs with different diameters and number of w...

Soft-sphere discrete element method (DEM) and Navier-Stokes equations were coupled with equations of energy for gas and solids to investigate the process of agglomeration in fluidized bed of polyethylene particles at high temperature. The Newton’s second law of motion was adapted for translational and rotational motion of particles and agglomerates. The cohesive force for polyethylene particles...

BACKGROUND Cell-penetrating peptides (CPPs) can act as carriers for therapeutic molecules such as drugs and genetic constructs for medical applications. The triggered release of the molecule into the cytoplasm can be crucial to its effective delivery. Hence, we implemented and characterized laser interaction with defined gold nanoparticle agglomerates conjugated to CPPs which enables efficient ...