Indigenous plants such as Ocimum Sancium, Aegle marmelos, Azadiracta indica, and Murraya koenigii decreased the blood sugar of streptozotocin diabetic rabbits. The most effective drug Aegle marmelos in different solvents showed different rate of hypoglycemic action. On feeding streptozotocin to diabetic rabbits for a period of 3 months aegle marmelos showed remarkable hypoglycemic action.

The aim of the current research was to evaluate the immunomodulatory potential of methanol extract of Aegle marmelos in an experimental animal model of cellular and humoral immunity. Administration of methanol extract of Aegle marmelos (500 and 1000 mg/kg, p.o.) and Ocimum sanctum (100 mg/kg, p.o.), produced significant increase in adhesion of neutrophils and an increase in phagocytic index in ...

Background: Polyelectrolyte complexes are complexes formed by interaction of two oppositely charged ions. This study deals with formation of chitosan–Aegle marmelos polyelectrolyte complex. Polyelectrolyte complex was found to be used as pharmaceutical excipient. Aim: The present study aimed to synthesize Chitosan–Aegle marmelos polyelectrolyte complex and their characterization and to compare ...

In the present study, possible cytochrome enzyme inhibition potential of Aegle marmelos (L.) Corrêa fruit and its bioactive compound was evaluated. Interaction potential of Aegle marmelos extract was evaluated through CYP450carbonmonoxide complex (CYP450-CO) assay. Additionally, influence on individual major human cytochrome P450 drug metabolizing enzymes such as CYP3A4, CYP2D6, CYP2C9 and CYP1...

OBJECTIVE To evaluate the in vitro antifungal activity of Aegle marmelos leaf extracts and fractions on the clinical isolates of dermatophytic fungi like Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum canis, Microsporum gypseum and Epidermophyton floccosum. METHODS The minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of various extracts and frac...

Aegle marmelos is a medicinal plant commonly known as bale. This plant contains different components of therapeutic value. The ethanolic extract of Aegle marmelos showed the presence of phytoconstituents like flavonoids, triterpenoids, coumarins, sterols, triterpenoids, alkaloids with other constituents. In present investigation, antibacterial, antifungal and wound healing effects of ethanolic ...

Oxidative stress induced by alloxan has been shown to damage pancreatic beta-cell and produce hyperglycemia in rats. Aegle marmelos leaf extract is being used in Ayurveda as a medicine for diabetes. The present study examined the action of Aegle marmelos against experimental diabetes as well as the antioxidant potential of the drug. A methanolic extract of Aegle marmelos was found to reduce blo...

In the present study, methanolic extracts of roots of Vitex negundo L. and extracts of leaves of Vitex negundo L., Ricinus communis L. and Aegle marmelos Corr. were explored for possible antifilarial effect against Brugia malayi microfilariae. It was observed that among the herbal extracts, root extract of Vitex negundo L. and leaves extract of Aegle marmelos Corr. at 100 ng/ml concentration sh...

In the present study the protective effects of Aegle mamelos fruit extract AMF were carried out in somatic cells of mice against doxyrubicin induced genotoxicity. Three different doses of Aegle Marmelos fruit extract were tested for the antimutagenicity using the micronucleus test in bone marrow cells of mice. The test compound doxyrubicin higher dose 16 mg/kg was injected intrapertioneally pri...

In this study ethanolic extract of Aegle marmelos was evaluated for its anti-ulcer activity against aspirininduced gastric ulcer in albino rats. Various biochemical parameters such as gastric volume, pH of gastric content, free acidity and total acidity, total carbohydrate content such as total protein, hexoses, hexosamine, fucose and sialic acid were estimated in alcoholic precipitate of gastr...