background: natural products have gained importance recently for the treatment of obesity and its complications, partly because of the side effects of modern drugs.hence, we aimed to study and compare the effect of varying concentrations of momordicacharantiaon adipogenesis and adipolysis using 3t3-l1 pre-adipocyte cell lines. methods: 3t3-l1 pre-adipocytes were procured from the national cente...

Background & Aim: Chorisia is an important Bombacaceous plant that is traditionally used for a variety of ailments. Due to its richness in several bioactive phytocompounds, some Chorisia species showed a wide range of important biological effects. Accordingly, the present work was undertaken to comparatively evaluate the antioxidant potential and effects on adipogenesis of <em...

Claussnitzer et al. claimed in previous work that a regulatory element within the first intron of FTO affects IRX3 and IRX5 expression during early adipogenesis. We present here formalization claim, stating all things class “early human adipogenesis” are context thing “regulatory FTO” generally have relation type “affects” to “expression genes IRX5” same context.

The purpose of this study was to prepare a clinical trial test material (ESETM, Ecklonia stolonifera extract) develop health functional food based on its anti-obesity effect. effect ESETM evaluated in 3T3-L1 adipocytes and obese mice fed high-fat diet (HFD) confirm nonclinical before application trial. Adipogenesis is process preadipocyte differentiation that causes an increase the production r...

background &amp; aim: chorisia is an important bombacaceous plant that is traditionally used for a variety of ailments. due to its richness in several bioactive phytocompounds, some chorisia species showed a wide range of important biological effects. accordingly, the present work was undertaken to comparatively evaluate the antioxidant potential and effects on adipogenesis of chorisia chodatii...

Background & Aim: Chorisia is an important Bombacaceous plant that is traditionally used for a variety of ailments. Due to its richness in several bioactive phytocompounds, some Chorisia species showed a wide range of important biological effects. Accordingly, the present work was undertaken to comparatively evaluate the antioxidant potential and effects on adipogenesis of <em...

PPARγ promotes adipogenesis while Wnt proteins inhibit adipogenesis. However, the mechanisms that control expression of these positive and negative master regulators of adipogenesis remain incompletely understood. By genome-wide histone methylation profiling in preadipocytes, we find that among gene loci encoding adipogenesis regulators, histone methyltransferase (HMT) G9a-mediated repressive e...

Obesity is recognized as a severe threat to overall human health and associated with type 2 diabetes mellitus, dyslipidemia, hypertension, cardiovascular diseases. Abnormal expansion of white adipose tissue involves increasing the existing adipocytes' cell size or number through differentiation new adipocytes. Adipogenesis process proliferation adipocyte precursor cells in mature As key determi...

BACKGROUND During mesenchymal stem cell (MSC) conversion into adipocytes, the adipogenic cocktail consisting of insulin, dexamethasone, indomethacin and 3-isobutyl-1-methylxanthine not only induces adipogenic-specific but also genes for non-adipogenic processes. Therefore, not all significantly expressed genes represent adipogenic-specific marker genes. So, our aim was to filter only adipogenic...

Gata transcription factors have been implicated in controlling adipogenesis in Drosophila and in mammals. In mammals, both Gata2 and Gata3 have been shown to be present in pre-adipocytes, and their silencing allows the onset of adipogenesis. Overexpression of Gata proteins blocks adipogenesis in cellular assays. Gata factors have been found to operate through recruiting cofactors of the Friend ...