objective(s): atherosclerosis is a chronic immune-inflammatory disease that generally leads to ischemic heart disease. ghrelin has several modulatory effects on cardiovascular system. in this study, we investigated the effect of ghrelin on aortic intima-media thickness, size and the number of adipocyte cells in obese and control mice. materials and methods:this study was conducted on 24 male c5...

objective(s): atherosclerosis is an important risk factor for coronary heart disease. neuropeptide y (npy) and its receptors, located in peripheral tissue such as white adipose tissue, have been linked to obesity and fat storage. the role of npy in atherosclerosis has not yet been fully studied, so this study was conducted to further investigate the effect of biie 0246, an npy receptor antagoni...

Objective(s): Atherosclerosis is a chronic immune-inflammatory disease that generally leads to ischemic heart disease. Ghrelin has several modulatory effects on cardiovascular system. In this study, we investigated the effect of ghrelin on aortic intima-media thickness, size and the number of adipocyte cells in obese and control mice. Materials and Methods:This study was conducted on 24 male C...

results the results showed that children with a higher weight z-score spend more time in sedentary activities and less time running or involved in active games. scd-1 activity index, arachidonic/linoleic index, and adipocyte volume were significantly higher in children with a weight z-score greater than 0. the preadipocyte number and the genetic expression of the studied genes did not differ be...

Objective(s): Atherosclerosis is an important risk factor for coronary heart disease. Neuropeptide Y (NPY) and its receptors, located in peripheral tissue such as white adipose tissue, have been linked to obesity and fat storage. The role of NPY in atherosclerosis has not yet been fully studied, so this study was conducted to further investigate the effect of BIIE 0246, an NPY receptor antagoni...

background: due to increasing clinical demand for adipose tissue, a suitable cell for reconstructive adipose tissue constructs is needed. in this study, we investigated the ability of human endometrial-derived stem cells (enscs) as a new source of mesenchymal stem cells to differentiate into adipocytes. enscs are the abundant and easy available source with no immunological response, for cell re...

introduction: fibrolipoma, a subtype of lipoma is painless, well-circumscribed, slow-growing, submucosal benign adipocyte tumour. it is uncommon in the oral cavity and oropharyngeal region, with rare incidence in the retropharynx even rarest in pediatric age group.   case report: a very unusual case of fibrolipoma is presented in a pediatric patient, who had a huge retropharyngeal fibrolipoma a...

Aim To optimize conventional coronary optical coherence tomography (OCT) images using the attenuation-compensated technique to improve identification of plaques and the external elastic lamina (EEL) contour. Methods and Results The attenuation-compensated technique was optimized via manipulating contrast exponent C, and compression exponent N, to achieve an optimal contrast and signal-to-nois...

background : many types of cancer cells require a supply of fatty acids (fa) for growth and survival, lpl, in the presence of triglyceride-rich lipoproteins, accelerates the growth of these cells. recent evidence shows that lpl plays important roles in inflammation and obesity, implies that it is an appropriate general target for chemo preventive and chemotherapeutic agents. thus, we reported l...

Adipose tissue expansion in obesity involves a series of cycles of adipocyte hyperplasia, hypertrophy and hypoplasia due to alterations in adipogenesis, adipocyte cellular metabolism and cell death, respectively. Increased frequency of these cycles may lead to deterioration of adipocyte function and viability, accelerated exhaustion of the adipocyte progenitor pool and extensive adipose tissue ...