Introducon: Acute hemorrhagic edema of infancy (AHEI) is a cutaneous leukocytoclas!c vasculi!s of infants, clinically characterized by acute development of peripheral edema and targetoid purpuric lesions on face and extremi!es. It is considered to be an uncommon form of cutaneous vasculi!s occurring in children younger than 2 years old. The clinical picture has a violent onset, a short beni...

Acute hemorrhagic edema of infancy (AHEI) is a rare skin disorder which was first described by Snow in 1913. Clinical manifestations are usually limited to cutaneous lesions and is most commonly observed in infants under the age of 1 year. Usually, there is a history of recent upper respiratory tract infection and antibiotic administration. Clinical presentation of this disease includes petechi...

Acute hemorrhagic edema of infancy is a cutaneous leukocytoclastic vasculitis, clinically characterized by the acute development of peripheral edema and targetoid purpuric lesions on the face and extremities. The clinical picture has a violent onset with a short benign course followed by spontaneous complete recovery. We describe a five-month-old boy with acute hemorrhagic edema, in whom the di...

Acute hemorrhagic edema of infancy is an unusual form of leukocytoclastic vasculitis occuring in children from the age 4 months to 2 years. The etiology remains unknown. Numerous studies, however, suggest acute hemorrhagic edema of infancy as an immune-mediated vasculitis in response to a variety of antigenic stimuli. We report a case of an acute hemorrhagic edema of infancy; 11-month-old boy w...

Acute Hemorrhagic Edema of Infancy is an infrequent leukocytoclastic vasculitis which occurs almost exclusively in children between 4 months and 2 years of age. It is clinically characterized by the triad fever, purpuric lesions on the face, auricular pinna and extremities, and edema. Although the cutaneous findings are dramatic and of rapid onset, the prognosis is favorable, with spontaneous r...

Acute hemorrhagic edema of infancy is a distinctive, cutaneous small vessel leukocytoclastic vasculitis of young children with dramatic characteristic skin findings. It is characterized by low- grade fever, erythematous edema, and purpuric lesions mainly on the face and extremities. Visceral involvement is uncommon, and spontaneous recovery usually occurs within one to three weeks without seque...

The authors report a case of acute hemorrhagic edema of infancy in an 8-month-old boy with a history of recent vaccination prior to the illness. He was well in general, apart from mild fever diarrhea, and the rash compatible with acute hemorrhagic edema of infancy; though, he had unusual trunk and mucosal involvement. The diagnosis was confirmed by the histopathological findings and direct immu...