AGEP: Acute generalized exanthematous pustulosis EBV: Epstein-Barr virus A cute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous reaction characterized by the acute onset of generalized nonfollicular sterile pustules arising on an edematous erythema. The eruption is usually associated with fever and neutrophilic leukocytosis. Although AGEP is precipitated by drugs in most ...

Acute generalized exanthematous pustulosis is an acute pustular eruption occurring most commonly after drug ingestion. It is a self-healing condition with spontaneous cure after discontinuation of the causative drug. We report the second case, as far as we know, of acute generalized exanthematous pustulosis induced by simvastatin intake. Conclusion: simvastatin can be included on the long list ...

Acute generalized exanthematous pustulosis (AGEP) is manifested by rapid development of many sterile, nonfollicular pustules on a background of edematous erythema. More than 90 percent of AGEP are induced by medication, mostly antibiotics. Drug patch test can be helpful in the diagnosis of AGEP. This paper reports the first case of celecoxib-induced AGEP confirmed by patch test in Korean litera...

Acute Generalized Exanthematous Pustulosis (AGEP) is a dermatosis characterised by an acute episode of appearance of sub-corneal sterile pustules over erythematous-edematous skin. AGEP is often associated with systemic symptoms such as high grade fever and is usually considered to be an adverse drug reaction, although a viral etiology is sometimes implicated. Here we report a case of AGEP follo...

Background Acute generalized exanthematous pustulosis (AGEP) is rare cutaneous drug reaction involving drug-specific T lymphocytes and neutrophilic inflammation. Imatinib is a tyrosine kinase inhibitor used widely in treatment of chronic myeloid leukemia (CML). Rash is a common side effect of imatinib, occurring in up to 30% of patients. However, there are only two case reports to date describi...

Duloxetine is a serotonin and norepinephrine reuptake inhibitor. Some rare duloxetine-induced hypersensitivity skin reactions have been reported. We report case of acute generalized exanthematous pustulosis potentially induced by duloxetine. Skin pustules appeared 8 days after the introduction Treatment with topical clobetasol propionate led to gradual remission lesions. As there are no cases p...

Acute generalized exanthematous pustulosis (AGEP) is the most common pustular rash. It a delayed immunological reaction involving cellular immunity and characterized by sudden, simultaneous onset of high fever scarlatiniform sheet erythema, which, in several hours, covered with numerous pustules lactescent content, non-follicular, sterile, predominant on face, trunk, folds. regresses less than ...

Daptomycin, a lipopeptide antibiotic with similar action as vancomycin, is used to treat complicated skin and soft tissue infections caused by resistant Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, penicillin-resistant streptococci, and vancomycin-resistant enterococci. Acute generalized exanthematous pustulosis (AGEP), characterized by acute onset of numerous ...