Acinetobacter is an aerobic, non-fermentative gramnegative bacillus, which is widespread in nature (1). Acinetobacter has been recognized as a pathogen which plays a significant role in the colonization and infection in immunocompromised patients. Acinetobacter has been implicated in a variety of nosocomial infections, including bacteremia, urinary tract infection, and ventilator-associated pne...

During the last years Acinetobacter species have emerged as clinically significant pathogens. Most infections are nosocomially acquired and mainly due to Acinetobacter baumannii. Little is known about the epidemiology and clinical significance of unnamed Acinetobacter species 3 (the second most often encountered member of the genus Acinetobacter) and other Acinetobacter species such as A. johns...

BACKGROUND Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA/RNA analogues that silence expression of specific genes. We studied whether PPMOs targeted to essential genes in Acinetobacter lwoffii and Acinetobacter baumannii are active in vitro and in vivo. METHODS PPMOs were evaluated in vitro using minimum inhibitory concentration (MIC) and viability assays...

Acinetobacter lwoffii, a nonfermentative gram-negative aerobic bacillus, which presents in the normal flora of the oropharynx and skin, has recently been reported as a cause of human infection. Herein, the authors present a case report of peritonitis related to automated peritoneal dialysis caused by A. lwoffii.

Bacteremia is currently one of the infections with the highest mortality in hospitals [1]. Acinetobacter lwoffii and Acinetobacter baumannii are gram-negative bacteria and both represent opportunistic pathogens. In certain cases, the management can be challenging since these organisms can be highly resistant to antimicrobial agents. Clinical illnesses associated with Acinetobacter include pneum...

BACKGROUND AND OBJECTIVES Acinetobacter causes a wide variety of illness in debilitated and hospitalized patients. Carbapenem resistance in Acinetobacter is an emerging problem and is a cause of concern as many nosocomial infections with Acinetobacter are resistant to most other antibiotics. The present study was aimed to study metallo-β-lactamase (MBL) production in Acinetobacter species. MA...

Acinetobacter species represent an important cause of nosocomial infections, producing urinary tract infections, pneumonia, endocarditis, wound infections, septicemia, meningitis. Acinetobacter were more frequent implicated in wounds infections (50.9%) and respiratory infections (20.4%). The infections prevalence was bigger in the Orthopedy (19.4%), Intensive Care Unit (18.5%) and Plastic Surge...

Three cryptic plasmids have been discovered in Acinetobacter calcoaceticus BD413. These three plasmids, designated pWM10 (7.4 kb), pWM11 (2.4 kb), and pWM12 (2.2 kb), exhibited extensive homology to one another, as shown by Southern blot hybridization and restriction site analysis data, and also hybridized with three plasmids having slightly different sizes detected in a second strain, A. calco...