A new insofar as chronobiologic therapeutic approach by atrial natriuretic peptide (ANP) for hypertension and/or congestive heart failure (CHF) is based on the release of ANP from ANP cDNA transfected Chinese Hamster Ovary (CHO) cells encapsulated in polycaprolactone (PCL) tubes. ANP secretion was maintained for at least 6 months. The encapsulated cells remained viable during culturing. Control...

This paper presents an integrated ANP and DEMATEL technique applied to identify and prioritize Six Sigma projects for healthcare companies. identify the most representative Six Sigma projects and their priority. First, the Six Sigma evaluation structure is determined; then DEMATEL (Decision Making Trial and Evaluation Laboratory) is applied to calculate interrelations among healthcare criteria....

To address this research possibility, the present empirical study undertakes assessment of usable-security healthcare software system. The attributes considered for are: four factors at first level; thirteen sub-factors second level with six Hospital Management Software Systems (HMSS) as alternatives. Fuzzy Analytic Network Process (F-ANP) has been applied evaluating weights and their relations...

Urodilatin is a recently described member of the atrial natriuretic peptide family, thought possibly to be synthesized in the kidney. To determine if urodilatin binding sites are present in rat and human kidney, we evaluated the effect of urodilatin on iodine-125-labeled atrial natriuretic peptide (ANP) (100 pM) binding to tissue sections using an in situ autoradiographic technique. 125I-ANP bi...

Atrial natriuretic peptide (ANP) is extensively expressed in the cochlea, including the strial vascularis (StV). ANP may participate in the regulation of the water-electrolyte balance. However, the functional significance of ANP in the cochlea is less understood and little is known regarding the exact mechanisms. Studies suggest that the epithelial sodium channel (ENaC) is important for regulat...

Decision making concept can be defined as selection process choosing one of the options, if the outcomes are not certain. In practice it is not sufficient to evaluate the options according to the simplest form of decision making only based on a criterion. In such cases, we must consider all the variety of different information to decide to best option. It arise the requirement of multi-criteria...

OBJECTIVE The aim of this study was to assess the efficacy of apical negative pressure (ANP), manual dynamic agitation (MDA), passive ultrasonic irrigation (PUI) and needle irrigation (NI) as final irrigation activation techniques for smear layer removal in curved root canals. MATERIALS AND METHODS Mesiobuccal root canals of 80 freshly extracted maxillary first molars with curvatures ranging ...

Synaptic inputs of corticotropin-releasing factor (CRF)-like Immuno reactive axon terminals to neurons containing atrial natriuretic peptide (ANP) in the anteroventral third ventricle (AV3V) region of the rat diencephalon were examined ultrastructurally by a pre-embedding double immunostaining technique combining the silver-gold intensified peroxidase-antiperoxidase complex-3,3'diaminobenzidine...

A striking aspect of many vertebrate immune system is the exceptionally high level of polymorphism they harbor. A convincing case can be made that this polymorphism is driven by the diversity of pathogens that face selective pressures to evade attack by the host immune system. Different organisms accomplish a defense against diverse pathogens through mechanisms that differ widely in their requi...

A monoclonal antibody to alpha-human atrial natriuretic polypeptide (alpha-hANP), KY-ANP-I, has been produced by fusion of a nonproducing mouse myeloma cell line, X63-Ag8.653, with spleen cells from BALB/c mice immunized with synthetic alpha-hANP conjugated to bovine thyroglobulin using the carbodiimide coupling procedure. Hybridomas were screened for antibody production by radioimmunoassay usi...