نتایج جستجو برای: 99mtc (v)

تعداد نتایج: 308051  

Journal: :Journal of neurology, neurosurgery, and psychiatry 1999
T J O'Brien B H Brinkmann B P Mullan E L So M F Hauser M K O'Connor J Hung C R Jack

OBJECTIVES Most studies that clinically validated peri-ictal SPECT in intractable partial epilepsy had used technetium-99m-hexamethylpropylene amine oxime (99mTc-HMPAO or 99mTc-exametazime) as the radiopharmaceutical. Because of some theoretical advantages, technetium-99m-ethyl cysteinate diethylester (99mTc-ECD or 99mTc-bicisate) is increasingly being used instead. This study compares unstabil...

2013
Runa H Poulsen Jan T Rasmussen June Anita Ejlersen Christian Flø Lise Falborg Christian W Heegaard Michael Rehling

BACKGROUND Phosphatidylserine (PS) is a phospholipid normally located in the inner leaflet of the cell membrane. PS is translocated from the inner to the outer leaflet of the plasma membrane during the early stages of apoptosis and in necrosis. In cell and animal studies, reversible PS externalisation to the outer membrane leaflet has been observed in viable cells. Hence, PS markers have been p...

Journal: :Cancer biotherapy & radiopharmaceuticals 2001
D J Yang A Azhdarinia P Wu D F Yu W Tansey S K Kalimi E E Kim D A Podoloff

OBJECTIVE The purpose of this study was to develop an imaging technique to measure and monitor tumor cells undergoing programmed death caused by radiation and chemotherapy using 99mTc-EC-annexin V. Annexin V has been used to measure programmed cell death both in vitro and in vivo. Assessment of apoptosis would be useful to evaluate the efficacy and mechanisms of therapy and disease progression ...

Journal: :Nuclear medicine review. Central & Eastern Europe 2012
Piotr Garnuszek Dariusz Pawlak Michał Maurin Drina Jankovic Urszula Karczmarczyk Renata Mikołajczak

BACKGROUND The reliable method for determination of identity and radiochemical purity (RCP) is of great importance in radiopharmaceutical development. This is especially relevant when more than one form of radiometal/ligand complex can be formed during radiolabelling, such as complexes of 99mTc or 188Re with meso-2,3-dimercaptosuccinic acid (DMSA), where depending on the pH, metal can occur eit...

Journal: :Oral oncology 2009
Ye Zhang Chuanbin Guo Guangyan Yu Chunli Zhang

This study compares the accuracy of 99mTc(V)-dimercaptosuccinic acid (99mTc(V)-DMSA) Single Photon Emission Computer Tomography (SPECT) by intravenous or local injection in the detection of occult cervical lymph node metastases in clinically N0 squamous cell carcinoma of the oral cavity. Fifty-eight previously untreated patients without clinically detectable cervical metastases were included in...

Journal: :Indian journal of experimental biology 2001
S Murugesan A P Banerji O P Noronha A M Samuel A O Fernandes

Purified field bean protease inhibitor (FBPI) was labeled with 99mTcO4- to ascertain its ability to locate tumors in tumor-bearing rat models. The labeling was done with Sn2+ as a reducing agent and the yield was 95%. It was stable for 2 hr at ambient temperature. The biodistribution study of the intravenously injected radiolabeled FBPI in normal Wistar rats at various time intervals showed a r...

Journal: :Hellenic journal of nuclear medicine 2013
Hamid Javadi Taghi Amiriani HoneySadat Mirkarimi Sima Besharat Shahriar Semnani Jamshid Abedi Mohammad Seyedabadi Majid Assadi

The clinical significance of pentavalent technetium-99m dimercaptosuccinic acid (99mTc(V)-DMSA) scintigraphy in diagnosing inflammatory bowel disease (IBD) has not yet been fully elucidated. The aim of this prospective paper was to study the above. This study included 54 patients, 22 females and 32 males (mean age: 36.68±11.49; range: 18-63 years) with IBD who came to our clinics for follow-up ...

2016
Vahid Basirat Zahra Azizi Sanam Javid Anbardan Mina Taghizadeh Asl Yasaman Farbod Azam Teimouri Nasser Ebrahimi Daryani

INTRODUCTION Due to limitation of colonoscopy in assessing the entire bowel and patients' intolerance in inflammatory bowel disease (IBD), in the current study, we aimed to prospectively compare the accuracy of 99mTc(V)-dimercaptosuccinic acid (DMSA) and fecal calprotectin with ileocolonoscopy as new methods for localizing inflammations. METHODS Current prospective study conducted between 2012 ...

Journal: :Cancer biotherapy & radiopharmaceuticals 2004
David Yang Masashi Yukihiro Dong-Fang Yu Megumi Ito Chang-Sok Oh Saady Kohanim Ali Azhdarinia Chang-Guhn Kim Jerry Bryant E Edmund Kim Donald Podoloff

PURPOSE The aim of this study was to evaluate 99mTc-ethylenedicysteine-glucosamine (EC-DG) for the assessment of tumor growth. METHOD To evaluate whether 99mTc-EC-DG is involved in cell nuclei activity, in vitro thymidine incorporation, and cell-cycle assays of EC-DG were conducted using lung and breast cancer cells. Biodistribution of 99mTc-EC-DG in lung tumor-bearing mice (0.5-4 hours, 1 Ci...

Journal: :iranian journal of nuclear medicine 2006
shahram dabiri oskooei

introduction: medullary thyroid carcinoma (mtc) is a rare thyroid cancer secreting calcitonin (ct) which is the most sensitive and specific tumor marker for mtc. this type of thyroid cancer is able to metastasize to different body areas including regional lymph nodes, lungs, liver and bone. the aim of this study was to assess the sensitivity and specificity of [99mtc-dmsa (v)] whole body scan (...

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