introduction: the lymphatic system provides one of the main paths for the spread (metastasis) of cancer from one part of body to another. hodgkin’s diseases, lymphocytic leukemia, various metastatic disease and many lymph node disorders can be assessed by lymphoscintigraphy. radionuclide lymphoscintigraphy has been used for many years to define lymphatic drainage of melanoma. the most common ra...

Introduction: The lymphatic system provides one of the main paths for the spread (Metastasis) of cancer from one part of body to another. Hodgkin’s diseases, lymphocytic leukemia, various metastatic disease and many lymph node disorders can be assessed by lymphoscintigraphy. Radionuclide lymphoscintigraphy has been used for many years to define lymphatic drainage of melanoma. The most com...

UNLABELLED Colloidal particle size is an important characteristic to consider when choosing a radiopharmaceutical for mapping sentinel nodes in lymphoscintigraphy. METHODS Photon correlation spectroscopy (PCS) and transmission electron microscopy (TEM) were used to determine the particle size of antimony trisulfide and rhenium sulfide colloids, and membrane filtration (MF) was used to determi...

The kinetics of lymph node and systemic uptake of members of three different classes of lymphoscintigraphic agents were studied in normal laboratory rats. 99mTc antimony trisulfide colloid (TcSbC), 99mTc human serum albumin (TcHSA), 125I 5G6.4 (a murine IgG2ak monoclonal antibody), 125I 763.24T (a murine IgG1), and 125I FT166 ( a murine IgM monoclonal) all current or potential lymphoscintigraph...

After intraventricular injection of 99mTc antimony sulfide in rabbits (n = 12) and cats (n = 14), radiolabeled colloid was imaged passing into the nasal mucosa and subsequently into the cervical lymph nodes. The cervical lymph nodes accounted for about 12% of the injected dose in rabbits sacrificed at 22-24 hr after injection and about 5% of the injected dose in cats sacrificed at 5-6 hr after ...

BACKGROUND Dual-tracer-guided sentinel lymph node (SLN) biopsy may provide a promising diagnostic tool to assess accurately the status of lymph node metastasis in the surgical operation and assure the oncologic safety of the function or stomach preserving surgery. The diagnostic performance of this technology in recent studies varied. Thus, we conducted this meta-analysis. METHODS This system...

BACKGROUND To study the value of periareolar intra-dermal injection of Tc-99m sestamibi (MIBI) for sentinel node mapping in breast carcinoma. MATERIAL AND METHODS Fifty patients with early-stage breast cancer were included in our study. 17.5 MBq Tc-99m-MIBI was injected intradermally to 25 patients and the remainders were injected with the same dose of Tc-99m-antimony sulphide colloid. Anteri...

Erysipelas (cellulitis/lymphangitis) is a superficial cutaneous infection spread by the lymphatic system which may result in permanent injury to the lymphatic vessels. The study evaluated the lymphatic drainage in the lower limbs of 30 patients with at least two episodes of erysipelas by means of lymphoscintigraphy. Twenty-two (73%) were female and 8 (27%) were male with ages ranging from 26 to...