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The CO dehydrogenase of the eubacterium Oligotropha carboxidovorans is a 277-kDa Mo- and Cu-containing iron-sulfur flavoprotein. Here, the enzyme's active site in the oxidized or reduced state, after inactivation with potassium cyanide or with n-butylisocyanide bound to the active site, has been reinvestigated by multiple wavelength anomalous dispersion measurements at atomic resolution, electr...
The Agrobacterium tumefaciens VirB proteins are postulated to form a transport pore for the transfer of T-DNA. Formation of the transport pore will involve interactions among the VirB proteins. A powerful genetic method to study protein-protein interaction is the yeast two-hybrid assay. To test whether this method can be used to study interactions among the VirB membrane proteins, we studied th...
OBJECTIVE To assess the effects of calcium channel blockers on development of infarcts, reinfarction, and mortality. DESIGN A systematic overview of all randomised trials of calcium channel blockers in myocardial infarction and unstable angina. PATIENTS 19,000 Patients in 28 randomised trials. RESULTS In the trials of myocardial infarction 873 deaths occurred among 8870 patients randomise...
CAIRNS, S.D., 1989:10:30. Discriminant analysis of Indo-West Pacific Flabellum. Mem. Ass. Australas. Palaeontols 8, 61-68. ISSN 0810-8889. Stepwise discriminant analysis was performed on 145 specimens of Indo-West Pacific Flabellum pertaining to 8 putative species. Posterior classification supported the premise of 8 species at the 99.3% level. Only two characters are needed to distinguish all s...
THE GEOGRAPHIC area inhabited by a species is constrained by its ecological niche, the multidimensional set of environmental variables that determines where members of a species can survive and maintain viable populations (Grinnell 1917). Individual organisms have the physiological capacity to inhabit any geographic location characterised by physical parameters within the constraints of the spe...
OBJECTIVES To introduce the UK SF36 Version II (SF36-II), and to (a) gain population norms for the UK SF36-II in a large community sample as well as to explore the instrument's internal consistency reliability and construct validity, and (b) to derive the Physical Component Summary (PCS) and Mental Component Summary (MCS) algorithms for the UK SF36-II. DESIGN Postal survey using a questionnai...
STUDY OBJECTIVE To examine the association between damp housing and adult health, taking into account a wide range of other factors that may influence health and could confound this relation. PARTICIPANTS AND SETTING A general population sample of adults, aged 18-64, from Oxfordshire, Buckinghamshire, Berkshire and Northamptonshire. DESIGN Secondary analysis of responses to a postal questio...
BACKGROUND Neonatal illness is a leading cause of death worldwide; sepsis is one of the main contributors. The etiologies of community-acquired neonatal bacteremia in developing countries have not been well characterized. METHODS Infants <2 months of age brought with illness to selected health facilities in Bangladesh, Bolivia, Ghana, India, Pakistan and South Africa were evaluated, and blood...
To reduce the burden of pneumococcal diseases, different formulations of pneumococcal conjugate vaccines (PCV) have been introduced in many countries. In Brazil, PCV10 has been available since 2010. We aimed to analyze the serotype and genetic composition of invasive pneumococci from Brazil in pre- and post-vaccination periods (2007-2012). Antibiotic susceptibility was determined and genotypes ...
1962 Gallager invents low density parity-check LDPC codes 1112 and what is now known as the sum-product iterative decoding algorithm for a p osteriori probability APP decoding. 1981 Tanner founds the eld of codes on graphs, introducing the bipartite graphical model now widely popular referred to as a Tanner graph" and the decoding algorithm now called the min-sum" or max-product" algorithm. Tan...
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