نتایج جستجو برای: 8.82%

تعداد نتایج: 1036  

Journal: :ACM Transactions on Mathematical Software 2008

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Journal: :Gynecologic oncology 2007
Daniel R Scoles James Pavelka Ilana Cass Hang Tran Rae L Baldwin Klara Armstrong Beth Y Karlan

OBJECTIVE Only a small number of comprehensively characterized immortalized ovarian cancer cell lines are available for laboratory studies on ovarian cancer. We describe a new ovarian cancer cell line that arose from primary culture of a stage IC, grade III ovarian carcinoma, designated CSOC 882. METHODS We characterized CSOC 882 by karyotyping, growth modeling, immunohistochemical staining, ...

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Journal: :Proteins 2012
Parthasarathy Sampathkumar Seung Joong Kim Danalyn Manglicmot Kevin T Bain Jeremiah Gilmore Tarun Gheyi Jeremy Phillips Ursula Pieper Javier Fernandez-Martinez Josef D Franke Tsutomu Matsui Hiro Tsuruta Shane Atwell Devon A Thompson J Spencer Emtage Stephen R Wasserman Michael P Rout Andrej Sali J Michael Sauder Steven C Almo Stephen K Burley

The nuclear pore complex (NPC), embedded in the nuclear envelope, is a large, dynamic molecular assembly that facilitates exchange of macromolecules between the nucleus and the cytoplasm. The yeast NPC is an eightfold symmetric annular structure composed of ~456 polypeptide chains contributed by ~30 distinct proteins termed nucleoporins. Nup116, identified only in fungi, plays a central role in...

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2006
Robert Fraser

This study is a review of the properties of protein planes. The basis of the research is the covalent bonds along the backbone of the protein, since the plane is defined by these atoms. We will measure the values of the bond lengths and the angles between the bonds to determine the consistency of these values in the PDB. We will go further to measure the lengths of the planes and omega, the dih...

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2016
Kathleen L Frisbee

BACKGROUND Mobile health (mHealth) technologies exhibit promise for offering patients and their caregivers point-of-need tools for health self-management. This research study involved the dissemination of iPads containing a suite of mHealth apps to family caregivers of veterans who receive care from the Veterans Affairs (VA) Health Administration and have serious physical or mental injuries. ...

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Journal: :Applied and environmental microbiology 2003
Jorge Frias-Lopez George T Bonheyo Qusheng Jin Bruce W Fouke

For 30 years it has been assumed that a single species of cyanobacteria, Phormidium corallyticum, is the volumetrically dominant component of all cases of black band disease (BBD) in coral. Cyanobacterium-specific 16S rRNA gene primers and terminal restriction fragment length polymorphism analyses were used to determine the phylogenetic diversity of these BBD cyanobacteria on coral reefs in the...

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Journal: :Cahiers d’histoire. Revue d’histoire critique 2015

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2016
Yuan-Bo Wu Di Lu Zhi-Feng He Chan-Guan Jin

Our study aimed to identify the association between a PIM1 polymorphism and PIM1 expression levels with clinicopathological features of esophageal squamous cell carcinoma (ESCC). A total of 168 patients with ESCC were recruited as the case group, and 180 healthy individuals were included as the control group. Polymerase chain reaction-direct sequencing was employed to analyze all genotypes cont...

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2004
THOMAS J. ROTHENBERG T. J. Rothenberg

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Journal: :Journal of managed care pharmacy : JMCP 2014
Jaime A Davidson

BACKGROUND Oral antihyperglycemic drugs used to treat type 2 diabetes mellitus (T2DM) vary in safety and tolerability. Treatment-related hypoglycemia and weight gain can exacerbate underlying disease.  OBJECTIVE To evaluate the tolerability of saxagliptin using data from phase III clinical trials.  METHODS Six 24-week randomized studies in 4,214 patients with T2DM were assessed. Saxagliptin...

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