To establish whether the use of proteinase inhibitors in the routine determination of in vitro plasma renin activity overestimates the potency of renin inhibitors in vivo, we examined the effects of phenylmethylsulfonyl fluoride and 8-hydroxyquinoline sulfate on the binding to plasma proteins and the respective IC50 values (50% inhibiting concentrations) of three renin inhibitors. All three ren...

Floriculture is among Kenya’s top foreign exchange earners. Gladiolus is one of the four famous cut flowers in the world whose popularity in Kenya is attributed to its heat tolerance, many spike forms and color combinations. However, the perishable nature of the flower renders it vulnerable to huge post-harvest losses. The study aimed to evaluate pulsing effect of cut Gladiolus</em...

The effects of savory, caraway, and rose extracts and 8-HQS were studied on the vase life of Alstroemeria cut flowers. The plant extracts at three levels (10, 20, and 40 %), 8-HQS at three levels (100, 200, and 300 mg l-1), and control (distilled water) with 3 % sucrose were continuously applied on the basis of a Completely Randomized Design with three replications. It was f...

Charge carrier dynamics in an organic semiconductor can often be described in terms of charge hopping between localized states. The hopping rates depend on electronic coupling elements, reorganization energies, and driving forces, which vary as a function of position and orientation of the molecules. The exact evaluation of these contributions in a molecular assembly is computationally prohibit...

8-Hydroxyquinoline and derivatives exhibit multifunctional properties, including antioxidant, antineurodegenerative, anticancer, anti-inflammatory and antidiabetic activities. In biological systems, elevation of intracellular calcium can cause calpain activation, leading to cell death. Here, the effect of 8-hydroxyquinoline and derivatives (5-chloro-7-iodo-8-hydroxyquinoline or clioquinol and 8...

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