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The RGD-binding α5 and αv integrins have been shown to be key regulators of vascular smooth muscle cell (vSMC) function in vitro. However, their role on vSMCs during vascular development in vivo remains unclear. To address this issue, we have generated mice that lack α5, αv or both α5 and αv integrins on their vSMCs, using the SM22α-Cre transgenic mouse line. To our surprise, neither α5 nor αv ...
http://bmj.com/cgi/content/full/321/7264/797 Updated information and services can be found at: These include: References http://bmj.com/cgi/content/full/321/7264/797#otherarticles 17 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/321/7264/797#BIBL This article cites 12 articles, 7 of which can be accessed free at: Rapid responses http://bmj.com/cgi/el...
A practical and effective strategy for synthesis of Folate-NIR 797-conjugated Magnetic Albumin Nanospheres (FA-NIR 797-MAN) was developed. For this strategy, Magnetic Albumin Nanospheres (MAN), composed of superparamagnetic iron oxide nanoparticles (SPIONs) and bovine serum albumin (BSA), were covalently conjugated with folic acid (FA) ligands to enhance the targeting capability of the particle...
The Rockefeller University Press $30.00 J. Cell Biol. Vol. 185 No. 5 797–810 www.jcb.org/cgi/doi/10.1083/jcb.200810084 JCB 797 Correspondence to Roger Reddel: [email protected] Z.-H. Zhong’s present address is Promega, Alexandria 2015, New South Wales, Australia. C.D. Toouli’s present address is Bio-Link Australia Pty Ltd, Locomotive Workshop, Eveleigh 2015, New South Wales, Australia. A...
Resistance categories (antibiosis and tolerance) of four sorghum (Sorghum bicolor (L.) Moench) hybrids to biotype I greenbug, Schizaphis graminum (Rondani), were determined in environmental growth chamber and field studies. Greenbug weight and fecundity were lower on ‘Cargill 607E’ compared with ‘Cargill 797’. Percentage of leaf damage area was significantly less on two resistant hybrids (Cargi...
The international migration of highly skilled professionals first emerged as a major public health issue in the 1940s, when many European health professionals emigrated to the United Kingdom and the United States. By the mid-1960s, the losses were enough to cause concern. In 1979, WHO published a detailed 40-country study on the magnitude and flow of health professionals, whose findings suggest...
Midline astroglia in the cerebral cortex develop earlier than other astrocytes through mechanisms that are still unknown. We show that radial glia in dorsomedial cortex retract their apical endfeet at midneurogenesis and translocate to the overlaying pia, forming the indusium griseum. These cells require the fibroblast growth factor receptor 1 (Fgfr1) gene for their precocious somal translocati...
Disturbances of neuronal excitability changes during the ovarian cycle may elevate seizure frequency in women with catamenial epilepsy and enhance anxiety in premenstrual dysphoric disorder (PMDD). The mechanisms underlying these changes are unknown, but they could result from the effects of fluctuations in progesterone-derived neurosteroids on the brain. Neurosteroids and some anxiolytics shar...
Background. The intestinal parasitic infections (IPIs) are globally endemic, and they constitute the greatest cause of illness and disease worldwide. Transmission of IPIs occurs as a result of inadequate sanitation, inaccessibility to potable water, and poor living conditions. Objectives. To determine a baseline prevalence of IPIs among children of five years and below at Webuye Health and Demo...
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