This is a report of the Project 1: Myautopano. In this project, we implemented an end-to-end pipeline to do image panorama stitching of images. This report will describe the basic idea of the algorithm using in this project and the corresponding results.

The recoveryphaseafterkidney ischemia/reperfusion(IR) injury isoften associated with the suppression of inflammation and the proliferation of tubular epithelial cells (TECs). The duration of this phase is often determined by the suppression of inflammation and the proliferation of TECs. Several lines of evidence suggest that IκB kinase α (IKKα) not only promotes the production of anti-inflammat...

The cellular basis of immunological memory remains a controversial issue. Here we show that basophils bound large amounts of intact antigens on their surface and were the main source of interleukins 6 and 4 in the spleen and bone marrow after restimulation with a soluble antigen. Depletion of basophils resulted in a much lower humoral memory response and greater susceptibility of immunized mice...

To represent the detected corners in a compact way, we use the following procedures: (1) Smooth the entire image using 5 × 5 Gaussian kernel with standard deviation 1. (2) Padding the image with a margin 20. (3) For each corner response, we crop a 41× 41 region, and reshape it to a one-dimensional vector. (4) Normalize the vector to zero mean and unit standard deviation. If we directly match th...

BACKGROUND CRC is a significant cause of cancer mortality, and new therapies are needed for patients with advanced disease. TAK-733 is a highly potent and selective investigational novel MEK allosteric site inhibitor. MATERIALS AND METHODS In a preclinical study of TAK-733, a panel of CRC cell lines were exposed to varying concentrations of the agent for 72 hours followed by a sulforhodamine ...

http://bmj.com/cgi/content/full/333/7571/733 Updated information and services can be found at: These include: Data supplement http://bmj.com/cgi/content/full/333/7571/733/DC1 "References" References http://bmj.com/cgi/content/full/333/7571/733#otherarticles 6 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/333/7571/733#BIBL This article cites 25 articl...

The goal of this study was to investigate the activity of the selective MEK1/2 inhibitor TAK-733 in both melanoma cell lines and patient-derived melanoma xenograft models. In vitro cell proliferation assays using the sulforhodamine B assay were conducted to determine TAK-733 potency and melanoma responsiveness. In vivo murine modeling with eleven patient-derived melanoma explants evaluated dail...

1 Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine, 733 N. Broadway, Edward D. Miller Research Building, Baltimore, MD 21205, USA; E-Mails: [email protected] (J.M.S.); [email protected] (J.E.C.) 2 Department of Neurology, The Johns Hopkins University School of Medicine, 733 N. Broadway, Edward D. Miller Research Building, Baltimore, MD 21205, U...

The effects of Simvastatin (MK-733), an inhibitor of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase, on fecal and biliary excretion of sterols and bile acids were examined using rabbits. Multiple doses of MK-733 (10 mg/kg/day) for 7 days were found to increase fecal concentrations of neutral sterols in cholesterol-fed rabbits, but not to affect those of bile acids. Multiple doses of cholest...