(i) Objective: This study was conducted to analyze the effect of lead acetate on the serum estrogen and progesterone levels in adult mice and the role of garlic extract. (ii) Study Design: Laboratory based Randomized Control Trial. (iii) Place and duration of study: Anatomy Department, Army Medical College, Rawalpindi in collaboration with National Institute of health from April-June 2013. (iv)...

The understanding of the molecular mechanisms of the immune tolerance induced by the tumoral microenvironment is fundamental to prevent cancer development or to treat cancer patients using immunotherapy. Actually, there are investigations about "addressed-drugs" against cancer cells without affecting normal cells. It could be ideal to find selective and specific compounds that only recognize an...

background: the main part of ovary is consisted of follicles which certain drugs may cause change in them. objectives: the purpose of this study was to investigate the effects of methylphenidate on ovarian follicle of mice, treated by ritalin before puberty. methods: 40 immature female mice at 3 weeks of age were divided into 4 groups, consisting of one control and 3 experimental groups. the ex...

phenol is widely used in numerous non prescription products and the aim of present study was to investigate the dose- dependent effects of phenol on morphometrical and histometrical changes of kidney in an animal model. for this experiment, 60 adult female balb/c mice were weighed, and categorrzed as one control and three experimental groups of 15 individuals each. control group, received only ...

By the age of 80 yr, the skeletal muscles of men and women decrease in mass and maximum force by approximately 30%. Severe contraction-induced injury may contribute to these age-related declines. One to two months after a 225 lengthening contraction protocol (LCP), muscles of young/adult male mice recovered completely, whereas those of old male mice sustained deficits of approximately 15% in ma...

Social stress may precipitate psychopathological disorders in susceptible individuals. The present experiments were focused on the biology beyond the differential susceptibility to social stress. Social defeat, an ethologically relevant stressor known to elicit different coping strategies, was used in two mouse strains differing for baseline emotionality, such as C57BL6/J and BalbC. In separate...

Article history: Received: 11 Apr 2012 Accepted: 21 Aug 2012 Available online: 5 Jan 2013 ZJRMS 2014; 16(3): 64-66 Background: Pomegranate juice has several antioxidant components such as flavenoids and mineral materials such as sodium and potassium. In this study the effects of pomegranate juice on bone calcium content and body weight of adult mice were survived. Materials and Methods: In this...