background: the present study compared lethal concentrations (lc50-96 h) of cdcl2, crcl3, and pb (no3)2 between two scaled and scaleless freshwater fish species: cyprinus carpio (cyprinidae) and pangasius hypophthalmus (pangasiidae). methods: the experimental fishes were obtained from fish markets/ponds with average lengths and weights of approximately 11.68 ±1.92 and 9.8±1.9 cm, and 25.92±6.3 ...

We have recently developed a data-mining pipeline that comprehensively identifies cancer unique susceptibilities, following the concept of Synthetic Lethality (SL). The approach enables, for the first time, to identify and harness genome-scale SL-networks to accurately predict gene essentiality, drug response, and clinical prognosis in cancer.

The partitioning of organic soil pollutants into soil organisms is driven by their chemical activity, which normally does not exceed that of the pure pollutant. Passive dosing with the silicone poly(dimethylsiloxane) (PDMS) was used to initiate and maintain the maximum chemical activity of 10 polycyclic aromatic hydrocarbons (PAHs) in toxicity tests with the springtail Folsomia candida. The tes...

Abstract Moringa oleifera leaves for traditional medicinal plants and as food has been widely used in Indonesia several regions the world by boiling using water a solvent before consumption. contain active compounds such phenols,flavonoids tannins. These can be helpful an antioxidant. The purpose of this study was to evaluate antioxidant activity lethality dose aqueous extract leaves. method ob...

in the present study, aqueous solutions of some copper-complexing ligands were screened for their cytotoxicity using brine shrimp lethality test. among the ligands tested, diacetyl-bis(n4-methylthiosemicarbazones) (atsm) proved to be the most safe and non-toxic compound (2% lethality at 10 ppm), while pyruvaldehyde bis(n4-methyl)thiosemicarbazone (ptsm) was shown to possess low toxicity (7% let...

objective(s): this study aimed to determine the possible toxicity of cuo nanoparticles (nps) on oncorhynchus mykiss by evaluating hematological parameters.materials and methods: fish were sampled and treated in 4 aquariums containing the concentration ranges of 1, 5, 20 and 100 ppm of cuo nps. there was one control group (no cuo nps) and three replicates. the physicochemical properties of water...

the effects of chronic administration of lithium, on acute toxicity of carbamazepine (cbz) in mate albino mice was studied and the ld50 values were determined from dose-probit curves. the results showed that in lithium pretreated animals (animals consumed drinking water contraining 600 mg/l lithium carbonate for 10 days) the ld50 value (the doese corresponding to probit 5) of cbz decreased sign...

Methamphetamine (MA) toxicity in aggregated mice was studied by varying the number of mice and the proportion of MA treated mice kept in the same confined space. The lethality was measured 24 h after intraperitoneal injections of MA at doses ranging from 10 to 100 mg/kg. MA lethality, over a wide dose range (15 to 50 mg/kg), was higher in aggregated mice than in those maintained in isolation. T...

the effects of chronic administration of lithium, on acute toxicity of chlorpromazine (cpz) in male albino mice was studied and the ldso values were determined from dose-probit curves. tfie results showed that in lithium pretrealed animals (anmials consumed drinking water containing 600mg/l lithium chloride for 10 days) the ld50 value (the dose corresponding to probit 5) of cpz increased signif...