The purpose of this presentation is to outline the Museum Multimedia (MM) experience in Russia. I am quite not sure wether all my colleagues experts and museum community in West Europe and America are intimately familiar with Russian experience in this sphere and I am pleased to have this opportunity to fill the gap. I will mainly focus on the general picture for some more reports with detailed...

Protein Description 393 amino acids; 53 kDa phosphoprotein; contains, from N-term to C-term, a transactivation domain, a DNA-binding domain, nuclear localization signals and a tetramerization domain. Expression Widely expressed. Localisation Nucleus. Function Tumour suppressor gene; P53 is a transcriptional regulator acting as a guardian of the genome; in response to DNA damage, p53 is overexpr...

Combined QM/MM calculations of an activesite of Cytochrome P450cam have been performed, before and after a binding process of Cytochrome P450cam to Putidaredoxin. The calculations have been carried out for two coordination spheres of the heme active-site of Cytochrome P450cam, namely a 5-coordinated, and a 6coordinated system of this protein having a water molecule as a 6th ligand. An experimen...

BACKGROUND AND PURPOSE Until now, endovascular treatment of symptomatic atherosclerotic stenosis in small intracranial arteries (≤2.5 mm) was limited. We evaluated the safety and efficacy of the treatment by using Wingspan stents in arteries of this caliber. MATERIALS AND METHODS From March 2007 to July 2010, 53 symptomatic intracranial stenoses with narrowing of at least 50% in 53 patients w...

BACKGROUND AND PURPOSE Thin-section noncontrast computed tomography images can be used to measure hyperdense clot length in acute ischemic stroke. Clots≥8 mm have a very low probability of intravenous tissue-type plasminogen activator recanalization and hence may benefit from a bridging intra-arterial approach. To understand the prevalence of such clots, we sought to determine the distribution ...