STUDY OBJECTIVE To compare the effect of a standardized stimulus during propofol-only hypnosis on the bispectral index (BIS) value with the effect of the injection of local anesthesia for surgery during ketamine plus propofol hypnosis (dissociative monitored anesthesia care). To determine whether ketamine increases the level of propofol hypnosis when used in dissociative doses. DESIGN Descrip...

This study examined the effects of 30% and 70% shading on growth characteristics, phenolic content, antioxidant activity three male cultivars (Atticus, Avalim, Herkolim) asparagus grown in a rain-shelter house. The treatment significantly increased shoot elongation rate all compared with control shade treatments. Compared treatment, production bud number Atticus Avalim cultivars. Most plant cha...

In this study, Rhizoclonium hieroglyphicum (C.Agardh) K tzing from the Nan River in northern Thailand was selected for investigation. The dried macroalga was extracted by water and 95% (v/v) ethanol to obtain an aqueous extract (RW) and ethanolic extract (RE), respectively. Each extract was examined for antimicrobial activity against Staphylococcus aureus ATCC 29213, methicillin resistant S. au...

Abstract Background In humans, various diseases are associated with the accumulation of free radicals. The antioxidants can scavenge radicals and reduce their impact; thus, search for effective natural plant origin is indispensable. present study aims to determine, first time, flavonoid compounds profile investigate radical scavenging antioxidant properties methanolic extract Taxus baccata L. f...

We investigated systematically the effects of Tet-induced oxidation products of 5-methylcytosine on Dnmt1- and DNMT3a-mediated cytosine methylation in synthetic duplex DNA. We found that the replacement of 5-methylcytosine at a CpG site with a 5-hydroxymethylcytosine, 5-formylcytosine, 5-carboxylcytosine or 5-hydroxymethyluracil resulted in altered methylation of cytosine at both the opposite a...

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

Nucleotide variants, especially those related to epigenetic functions, provide critical regulatory information beyond simple genomic sequence, and they define cell status in higher organisms. 5-Methylcytosine, which is found in DNA, was until recently the only nucleotide variant studied in terms of epigenetics in eukaryotes. However, 5-methylcytosine has turned out to be just one component of a...

Cytosine can undergo modifications, forming 5-methylcytosine (5-mC) and its oxidized products 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine (5-fC) and 5-carboxylcytosine (5-caC). Despite their importance as epigenetic markers and as central players in cellular processes, it is not well understood how these modifications influence physical properties of DNA and chromatin. Here we report a co...