Abstract The neurotrophin Brain-derived neurotrophic factor (BDNF) is encoded by multiple bipartite transcripts. Each BDNF transcript composed one out of 11 alternatively spliced exons containing the 5′untranslated region (UTR), and common exon encompassing coding sequence (CDS) 3′UTR with two variants (short long). In neurons, mRNA have a distinct subcellular distribution, constituting “spatia...

Dynein axonemal light intermediate chain 1 (dnali1) is an important part of dyneins and plays role in the growth development animals. However, there little information about dnali1 fish. Herein, we cloned gene from genome olive flounder (Paralichthys olivaceus), a commercially maricultured fish China, Japan, Korea, analyzed its expression patterns different gender The DNA sequence contained 771...

Objective(s):OCT4 is a transcription factor required for pluripotency during early embryogenesis and the maintenance of identity of embryonic stem cells and pluripotent cells. Therefore, the effective expression regulation of this gene is highly critical. UTR regions are of great significance to gene regulation. In this study, we aimed to investigate the potential regulatory role played by 5´UT...

objective: hepatitis c virus is the major cause of viral hepatitis and its diagnosis in suspected specimens is of great importance. the risk of transfusion- transmitted virus infection is primarily the result of failure in serological screening tests to detect recently infected donors in the pre-seroconversion window period of infection. therefore, sensitive and accurate diagnosis of hcv prior ...

background torque teno virus (ttv) belongs to the circoviridae family and was separated from japanese patients with elevated levels of serum alanine transferase for the first time. following this, extensive studies have been carried out around the world. objectives the present study was designed to investigate and determine the frequency of ttv genotypes in patients with chronic hepatitis b and...

Mutation in the dystrophin gene results Duchenne Muscular Dystrophy (DMD), an X-linked fatal neuromuscular disorder. Dystrophin deficiency can be compensated by upregulation of utrophin, an autosomal homologue of dystrophin. But the expression of utrophin in adults is restricted to myotendinous and neuromuscular junctions. Therefore utrophin upregulation throughout the muscle fiber can only be ...

The present study was conducted on the Nile tilapia (Oreochromis niloticus) and screened for single nucleotide polymorphisms (SNPs) in muscle hormone genes myogenin (MyoG) myostatin (MSTN). Samples were collected from JangHang fish farm categorized by body weight sex. average total 1.02 kg 82 males 0.63 70 females. A range of ±10% considered as normal weight. Target regions each gene categorize...