Protein Description 393 amino acids; 53 kDa phosphoprotein; contains, from N-term to C-term, a transactivation domain, a DNA-binding domain, nuclear localization signals and a tetramerization domain. Expression Widely expressed. Localisation Nucleus. Function Tumour suppressor gene; P53 is a transcriptional regulator acting as a guardian of the genome; in response to DNA damage, p53 is overexpr...

We consider an ideal gas of massive hadrons in thermal and chemical equilibrium. The gas expands longitudinally in an adiabatic way. This evolution for a baryonless gas reduces to a hydrodynamic expansion. Cooling process is parametrized by the sound velocity. The sound velocity is temperature dependent and is strongly influenced by hadron mass spectrum. ∗Work partially supported by the Polish ...

This paper is an introductory guide to many-particle hydrodynamic interactions. Basic concepts of the fluid mechanics are assumed to be known. Experience in the Stokes equations is useful but not necessary. The study is estimated to fit five sessions about three hours each. Auguste Rodin: “Nothing else that I have done satisfies me as much, because nothing else cost me so much effort...”[**]

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The accelerating trend toward Faster, Better, Cheaper (FEE) missions places increasing emphas is on the trade-offs between requirements and risk to reduce cost and development times, while still improving quality and reliability. The Risk/Requirenlents Trade-off Guidelines discussed in this paper are part of an integrated approach to address the main issues by focusing on the sum of prevention,...