CuO, Fe2O3, MnO2 and ZnO substituted 45S5 bioactive glasses were prepared. Glass derived Bioactive Glass ceramics were obtained through controlled crystallization of bioactive glasses. The formed crystalline phases in bioactive glass ceramics were identified using X ray diffraction (XRD) analysis. Density and ultrasonic wave velocities of bioactive glasses and glass ceramics were measured and u...

-The bioactive glass 45S5 (Hench glass), having composition 45 SiO2 24.5 Na2O 24.5 CaO -6 P2O5 (wt %) were prepared with substituted Li2O, K2O, ZnO, MgO, and B2O3 by conventional melting process in an electric globar furnace at 1400±10 OC. The Controlled crystallization were carried out to convert the bioglasses to their corresponding bioglass ceramics. Nucleation and crystallization regimes we...

Abstract — Fe2O3 substituted 45S5 bioactive glasses were prepared. Glass derived Bioactive Glass ceramics were obtained through controlled crystallization of bioactive glasses. Nucleation and crystallization regimes were determined by the parameters obtained from differential thermal analysis (DTA) of bioactive glasses. The formed crystalline phases in bioactive glass ceramics were identified u...

Bioactive glass is used as both a bone filler and as a coating on implants, and has been advocated as a potential osteogenic scaffold for tissue engineering. Rat-derived mesenchymal stem cells (MSCs) show elevated levels of alkaline phosphatase activity when grown on 45S5 bioactive glass as compared to standard tissue culture plastic. Similarly, exposure to the dissolution products of 45S5 elev...

INTRODUCTION: Osteoporotic patients, smokers and diabetics are among those who represent higher risks with regard to bone formation. In these clinical situations where bone regeneration can be especially difficult there is a need for an active agent or material which can stimulate osteoblasts in addition to providing a scaffold for growth. Extensive research has been performed on silicon and ca...

Bioactive glasses are known to stimulate bone healing, and the incorporation of strontium has the potential to increase their potency. In this study, calcium oxide in the 45S5 bioactive glass composition was partially (50%, Sr50) or fully (100%, Sr100) substituted with strontium oxide on a molar basis. The effects of the substitution on bioactive glass properties were studied, including density...

In this research work, the original 45S5 bioactive glass was modified by introducing zinc and/or strontium oxide (6 mol%) in place of calcium oxide. Sr was added for its ability to stimulate bone formation and Zn for its role in bone metabolism, antibacterial properties, and anti-inflammatory effect. The glasses were produced by means of melting and quenching process. SEM and XRD analyses evide...

Submit Manuscript | http://medcraveonline.com only osteoconductivity but also osteoinductivity, has attracted much interests in the field of bone tissue engineering but not only. Indeed, the typical silicate bioactive glasses demonstrated to bond to bone more efficiently than any other synthetic materials [1]. However, it was rapidly found that the highly disrupted silica network of bioactive g...

PURPOSE To determine the abrasivity of a 45S5 bioactive glass based toothpaste on enamel as a function of the particle size and shape of the glass. METHODS 45S5 glass was synthesized ground and sieved to give various particle sized fractions < 38, 38-63 and 63-110 microns. Two different grinding routes were used: percussion milling and ball milling. The glass powders were formulated into toot...