5,5-Dimethylcyclohexane-1,3-dione was treated with semicarbazide to yield its acid hydrazide, which on further reaction under ultrasound condition with aryl isothiocyanates gave 1,3-bis-imino-[1-(carboxy)-4-substituted phenylthiosemicarbazide]-5,5-dimethylcyclohexane. This compound in acidic medium gave 1,3-bis-imino-[5-(substituted) phenylamino-1,3,4-thiadiazol-2-yl-]-5,5-dimethylcyclohexane, ...

A number of 1,3,4-oxadiazole, 3-9, and 1,2,4-triazole derivatives, 13-15, were synthesized starting form the acid hydrazide 1. The 1,3,4-thiadiazole derivative 12 was prepared from the substituted phenylthiosemicarbazide derivative 11 by treatment with sulfuric acid. The aryl hydrazone derivatives 10a-c were synthesized by reaction of the hydrazide 1 with the corresponding ketones. The thioalky...