The reaction of P-diketones 1 with phenyl hydrazine afforded 5-aryl-3-(1- methyl-5-nitro-2-imidazoly1)-1-phenylpyrazole (2) and 3-aryl-5-(1-methyl-5- nitro-2-imidazoly1) -1-phenylpyrazole (3). The reaction of diketones (1) with urea in the presence of p-toluenesulfonic acid gave 4-(or 6-)aryl-6-(or 4-)(1-methyl- 5-nitro-2-imidazolyl)-1-(lH)pyrimidones (4). The structures of all compounds w...

Abstract The direct arylation of 1,3‐benzodioxole and 2,2‐difluorobenzo[1,3]dioxole with 26 different aryl bromides yields the respective 4‐substitued products in >80% requiring between 0.05–1 mol % Na 2 PdCl 4 , 30 pivalic acid, 1.3 equivs. K CO 3 ca. 250 diethylacetamide per Pd at T =120 °C. nature amide concentration reactants are crucial for optimization reaction conditions. primary role...

This paper studies John 4: 1-26 in a post-structuralist hermeneutical perspective. Hermeneutics is the art of understanding, namely understanding text, aiming to reveal meaning contained text. In this case, what meant hermeneutics which assumes that text lies not behind but front it. With assumption, beyond author's interests, thus opening up possibility for polysemy found by reader today. Four...

the reaction of p-diketones 1 with phenyl hydrazine afforded 5-aryl-3-(1- methyl-5-nitro-2-imidazoly1)-1-phenylpyrazole (2) and 3-aryl-5-(1-methyl-5- nitro-2-imidazoly1) -1-phenylpyrazole (3). the reaction of diketones (1) with urea in the presence of p-toluenesulfonic acid gave 4-(or 6-)aryl-6-(or 4-)(1-methyl- 5-nitro-2-imidazolyl)-1-(lh)pyrimidones (4). the structures of all compounds were c...

New efficient synthetic methods in pyrazoline and pyrazolopyrazine chemistry have been developed starting from 2,2-dichlorovinylacetophenones 1, which were sequentially transformed into 3-aryl-5-dichloromethyl-1-(2-hydroxiethyl)-2-pyrazolines 2, 3-aryl-5-dichloromethyl-1-(2-O-tosylhydroxyethyl)-2-pyrazolines 3, 3-aryl-5-dichloromethyl-1-(2-azidoethyl)-2-pyrazolines 4, 3-aryl-5-dichloromethyl-1-...

Abstract We report the synthesis of 4‐aryl‐2‐piperidone, 4‐arylpiperidine motifs, antituberculosis molecule Q203 (Telacebec) and its analogues. Direct lactamization β ‐C−H arylated N ‐phthaloyl δ ‐aminopentanoic acid carboxamides yielded 4‐aryl‐2‐piperidone (4‐aryl‐ ‐valerolactam) scaffolds. The required were assembled via Pd(II)‐catalyzed, 8‐aminoquinoline‐aided, sp 3 activation arylation meth...

Reactions of the aryl complexes Rh(aryl){? 3 -P,O,P-[xant(P i Pr 2 ) ]} (1; = 3,5-Me C 6 H (a), 5 (b), 3,5-Cl (c), 3-FC 4 (d); xant(P 9,9-dimethyl-4,5-bis-(diisopropylphosphino)xanthene) with O , CO, and MeO CC?CCO Me have been performed. Under 1 atm pentane solutions afford dinuclear peroxide derivatives [Rh(aryl){? -P,P-xant(P }] (?-O (2a–2d) as yellow solids. In solution, these species are u...

pathogenic infections and inflammation are very common ailments humans suffer. upsurge of resistant pathogens has impeded the antimicrobial drug development process in recent years and the search of new antimicrobial agents is clearly evident from the literature. in line with these developments the synthesis of n-substituted aryl-2-({4-[(substituted aryl carbamoyl) methyl]-5-(pyridin-4-yl)-4h-1...

Pathogenic infections and inflammation are very common ailments humans suffer. Upsurge of resistant pathogens has impeded the antimicrobial drug development process in recent years and the search of new antimicrobial agents is clearly evident from the literature. In line with these developments the synthesis of N-substituted aryl-2-({4-[(substituted aryl carbamoyl) methyl]-5-(pyridin-4-yl)-4H-1...