The Rockefeller University Press $30.00 J. Gen. Physiol. 2017 Vol. 149 No. 4 431–441 https://doi.org/10.1085/jgp.201611726 43

To identify volatile constituents in Typhonium giganteum Engl., and clarify their effects on proliferation of breast cancer T47D cell lines. Volatile constituents in Typhonium giganteum Engl. are extracted by steam distillation, and determined by GC-MS. 24, 48 and 72 h after treatment of T47D cells with different concentrations of Typhonium giganteum Engl. volatile (DJL-V) constituents, methyl ...

The requirement of leukemia inhibitory factor (LIF) for theestablishment and maintenance of mouse embryonic stem cells (ESCs) depends on thegenetic backgroundof theESCorigin. To reveal themolecular basis of the strain-dependent function of LIF, we compared the activation of the intracellular signaling pathways downstream of LIF in ESCs with different genetic backgrounds. We found that the JAK-S...

The association of heat-stable enterotoxin (STa) produced by enterotoxigenic Escherichia coli 431 with isolated rat intestinal epithelial cells and brush border membranes was characterized. Specific binding of strain 431 125I-STa to a single class of specific high-affinity receptors was saturable and temperature dependent and reached a maximum between 5 and 10 min. A 1,000-fold excess of unlabe...

A reinvestigation of a Fijian collection of Cacospongia mycofijiensis has yielded the known mycothiazole and a novel heterocyclic, CTP-431 (1). Its structure including absolute configuration as 8R,9R,10S,13S was established using NMR data, calculated DFT (13)C chemical shifts and results from X-ray crystallography. It is possible that the tricyclic skeleton of CTP-431 (1) is biosynthetically re...

The problem of ricochet of any projectile when it fails to hit the target or ifter its impact on the target, is of great importawe for the services as well as for the police personnel. The ricochet process is of constant concern for the Airforce authorities also during air to ground attack, due to the chances of hit to own a h a & from own fire. Whenever any bullet hits the pound short of targe...