We examined the effects of KW-3635, a thromboxane (TX) A2-receptor antagonist, and OKY-046, a TX synthetase inhibitor, on the prostaglandin (PG) I2 production in endothelium-intact and -injured guinea pig aorta and compared them with those of aspirin. In the endothelium-intact aorta, both the low (3 mg/kg) and the high (100 mg/kg) dose of aspirin similarly reduced the PGI2 production, as measur...

Stevens et al., (2021). AstronomicAL: an interactive dashboard for visualisation, integration and classification of data with Active Learning. Journal Open Source Software, 6(65), 3635, https://doi.org/10.21105/joss.03635

Word Count: 197 Total Text Word Count: 4989 Scientific Heading: Immunobiology Blood First Edition Paper, prepublished online May 6, 2004; DOI 10.1182/blood-2003-10-3635 Copyright (c) 2004 American Society of Hematology For personal use only. on October 3, 2017. by guest www.bloodjournal.org From

Department of Screening for Gastrointestinal Cancer 1 , Department of Cancer Epidemiology2, Department of Gastroenterology3, Department of Epidemiology and Mass Examination of Cardiovascular Diseases4, Osaka Medical Center for Cancer and Cardiovascular Diseases. 3-3 Nakamichi 1-Chome, Higashinari-Ku, Osaka 537-8511, Japan; Department of Hygiene and Preventive Medicine, Osaka University School o...

CHAPMAN, A. R., P. W. HODGES, A. M. BRIGGS, P. J. STAPLEY, and B. VICENZINO. Neuromuscular Control and ExerciseRelated Leg Pain in Triathletes. Med. Sci. Sports Exerc., Vol. 42, No. 2, pp. 233–243, 2010. Previous studies have shown that cycling can directly influence neuromuscular control during subsequent running in some highly trained triathletes. A relationship between this altered neuromusc...

reproductive age.3 However, other empirical evidence has indicated that state abortion restrictions have no such impact.4 The relationship between state-level abortion policies and birthrates is even murkier. Since the birthrate is the product of the pregnancy rate and the ratio of births to pregnancies, state abortion policies may affect birthrates by influencing one or both of these factors. ...

Advanced single-cell analysis technologies (e.g., mass cytometry) that help in multiplexing cellular measurements in limited-volume primary samples are critical in bridging discovery efforts to successful drug approval. Mass cytometry is the state-of-the-art technology in multiparametric single-cell analysis. Mass cytometers (also known as cytometry by time-of-flight or CyTOF) combine the cellu...