Recently, we found that Streptomyces olivochromogenes NBRC 3561 produced a bioactive peptide, so we sequenced its genome to clarify its biosynthesis. We report here the draft genome sequence of S. olivochromogenes NBRC 3561, in which 40 potential secondary metabolite gene clusters were predicted by antiSMASH.

Through intercellular signalling, the somatic compartment of the foetal testis is able to program primordial germ cells to undergo spermatogenesis. Fibroblast growth factor 9 and severalmembers of the transforming growth factor β superfamily are involved in this process in the foetal testis, counteracting the induction of meiosis by retinoic acid and activating germinal mitotic arrest. Here, us...

Abstract. – OBJECTIVE: Accumulating evidence revealed that long non-coding RNAs (lncRNAs) were emerging regulators in cancer biology, and could be used as potential biomarkers for cancer prognosis. In this study, we focused on MALAT1 and investigated its expression pattern, clinical significance in osteosarcoma. PATIENTS AND METHODS: The expression of lncRNA MALAT1 was analyzed in 162 osteosarc...

RhoGEFs play an important role in various signaling cascades and are implicated in human conditions like cancer and mental retardation. A database search combined with screening of a human neuronal teratocarcinoma library identified two novel RhoGEFs, ARHGEF3 and ARHGEF4 (HGMW-approved symbols). The widely expressed ARHGEF3 transcript of 3561 nucleotides encodes a polypeptide of 526 amino acids...

Validation of an ELISA for the diagnosis of human trichinellosis 1 2 Running title: Serodiagnosis of human trichinellosis 3 4 Maria Angeles Gómez-Morales, 1* Alessandra Ludovisi, 1 Marco Amati, 1 Simona Cherchi, 1 5 Patrizio Pezzotti, 2 and Edoardo Pozio 1 6 7 Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di 8 Sanità, 1 and Agenzia di Sanità Pubblica, 2 Rom...

The 3561 m Vostok ice core sample originating from the subglacial Lake Vostok accretion (frozen lake water) ice with sediment inclusions was thoroughly studied by various means to confirm the presence of the thermophile bacterium Hydrogenophilus thermoluteolus reported earlier in the 3607 m accretion ice sample. PCR and molecular-phylogenetic analyses performed in two independent laboratories w...

Intracranial meningeal hemangiopericytomas in children and adolescents are prone to bleeding during surgery. CT and MR imaging may serve a role in preoperative diagnosis. The purpose of this report was to describe the radiologic findings in 9 pathologically proved cases of intracranial meningeal hemangiopericytomas in children and adolescents. The average duration of symptoms was short (mean, 4...

Field experiment was conducted using 64 genotypes of foxtail millet to assess the genetic divergence for 24 metric traits in Kharif 2020. The ANOVA revealed existence highly significant variation all examined. Principal component analysis identified nine principal components with eigen value more than one and 76.59% cumulative variance. 2D 3D plots indicated that SiA 60, 3570, 3914, 3222, 3629,...