background: medical plants have been recently used to treat diabetes. osteoporosis is one of diabetes side effects and increases the risk of bone fracture in diabetic patient. objectives: the purpose of the present study was to investigate the potential bone protective effects of o.persica ethanolic extract in streptozotocin-induced diabetic rats. methods: forty male rats were randomly divided ...

DOI: 10.21276/sjams.2017.5.9.49 Abstract: Evolvulus alsinoides Linn. Is a medicinal plant that belongs to the family convolvulaceae. This study seeks to evaluate the effects of the aqueous extract of Evolvulus alsinoides Linn. on sperm parameters and the testis. A total of fifty (50) Wistar albino rats weighing 135-150g were used in this research. The rats were divided into five (I-V) Groups of...

BACKGROUND Conflicting reports about the toxicity of Synedrella nodiflora (L) Gaertn (family Asteraceae), a plant traditionally used in Ghana for the management of epilepsy, abound in literature. The present study evaluates the effect of a 90-day continuous oral administration of a hydro-ethanolic whole plant extract of Synedrella nodiflora (SNE) in male Sprague-Dawley rats. METHODS The toxic...

In this study, the hepatoprotective effect of the methanol extract of aerial parts (shoot) from Otostegia persica Boiss (Golder) was investigated against the carbon tetrachloride (CCl4)-induced acute hepatotoxicity in male rats. Liver damage was induced through the oral administration of 50% CCl4 in liquid paraffin (2.5 mL/Kg bw, per os) 60 min after the administration of the methanol extract o...

In this study, the hepatoprotective effect of the methanol extract of aerial parts (shoot) from Otostegia persica Boiss (Golder) was investigated against the carbon tetrachloride (CCl4)-induced acute hepatotoxicity in male rats. Liver damage was induced through the oral administration of 50% CCl4 in liquid paraffin (2.5 mL/Kg bw, per os) 60 min after the administration of the methanol extract o...

Nephrotoxicity remains a common untoward effect of cisplatin therapy with limited effective chemopreventive options available till date. This study aims to evaluate the possible chemopreventive effect and mechanism(s) of action of 2 mgkg-1 and 5 mgkg-1 of Tadalafil in cisplatin-induced nephrotoxic rats. In this study, twenty-five male Wistar rats were randomly divided into five groups (n = 5 ra...

in this study, the hepatoprotective effect of the methanol extract of aerial parts (shoot) from otostegia persica boiss (golder) was investigated against the carbon tetrachloride (ccl4)-induced acute hepatotoxicity in male rats. liver damage was induced through the oral administration of 50% ccl4 in liquid paraffin (2.5 ml/kg bw, per os) 60 min after the administration of the methanol extract o...

In this study, the hepatoprotective effect of the methanol extract of aerial parts (shoot) from Otostegia persica Boiss (Golder) was investigated against the carbon tetrachloride (CCl4)-induced acute hepatotoxicity in male rats. Liver damage was induced through the oral administration of 50% CCl4 in liquid paraffin (2.5 mL/Kg bw, per os) 60 min after the administration of the methanol extract o...

BACKGROUND Heliotropium indicum is used as a traditional remedy for hypertension in Ghana. The aim of the study was to evaluate the anti-glaucoma potential of an aqueous whole plant extract of H. indicum to manage experimentally-induced glaucoma. METHODS The percentage change in intraocular pressure (IOP), after inducing acute glaucoma (15 mLkg(-1) of 5 % dextrose, i.v.), in New Zealand White...