In the mol-ecule of the title compound, C(10)H(10)N(2)O(2), the rings are nearly coplanar, making a dihedral angle of 2.35 (5)°. In the crystal structure, inter-molecular C-H⋯O, C-H⋯N and O-H⋯O hydrogen bonds link the mol-ecules, generating R(4) (4)(22) and R(4) (4)(24) ring motifs to form a three-dimensional network. A weak π-π inter-action between the pyridazinone and benzene rings further st...

Ionic liquids such as 1,3-dialkylimidazolium salts make excellent catalysts and solvents for synthesis of dialkyl 2-(dialkoxyphosphoryl)-3-(1-oxo-1-H-phthalazin-2-yl)succinates from 2H-phthalazin-1-one, dialkyl acetylenedicarboxylates, and trialkyl phosphites. Under similar conditions, triphenyl phosphite led to dialkyl 2-(diphenoxyphosphoryl)-3-(1-oxo-1-H-phthalazin-2-yl)succinates. The ionic ...

A novel strategy for the construction of the phthalazin-1(2H)-one scaffold has been developed by means of a copper-mediated cascade C-H/C-H coupling and intramolecular annulations and a subsequent facile hydrazinolysis. This C-H activation transformation proceeds smoothly with wide generality, good functional tolerance and high stereo- and regioselectivity under mild conditions. Through the rem...

Ionic liquids such as 1,3-dialkylimidazolium salts make excellent catalysts and solvents for synthesis of dialkyl 2-(dialkoxyphosphoryl)-3-(1-oxo-1-H-phthalazin-2-yl)succinates from 2H-phthalazin-1-one, dialkyl acetylenedicarboxylates, and trialkyl phosphites. Under similar conditions, triphenyl phosphite led to dialkyl 2-(diphenoxyphosphoryl)-3-(1-oxo-1-H-phthalazin-2-yl)succinates. The ionic ...