AM-2201 is a synthetic cannabinoid that acts as a potent agonist at cannabinoid receptors and its abuse has increased. However, there are no reports of the inhibitory effect of AM-2201 on human cytochrome P450 (CYP) or uridine 5'-diphospho-glucuronosyltransferase (UGT) enzymes. We evaluated the inhibitory effect of AM-2201 on the activities of eight major human CYPs (1A2, 2A6, 2B6, 2C8, 2C9, 2C...

Author’s affiliations: S. Gomez, Health Research and Policy, Stanford University School of Medicine, Stanford, California; Northern California Cancer Center, 2201 Walnut Ave, Suite 300, Fremont, California 94538, [email protected]. C. O’Malley, Northern California Cancer Center, 2201 Walnut Ave, Suite 300, Fremont, California 94538 (affiliation at time of work), [email protected] A. Stro...

We report the discovery of the most distant known AGN, the radio galaxy TN J0924−2201 at z = 5.19. The radio source was selected from a new sample of ultra–steep spectrum (USS) sources, has an extreme radio spectral index α 365MHz = −1.63, and is identified at near–IR wavelengths with a very faint, K = 21.3± 0.3 object. Spectroscopic observations show a single emission line at λ ∼ 7530 Å which ...

Core Based Trees (CBT) Multicast Routing Architecture Status of this Memo This memo defines an Experimental Protocol for the Internet community. This memo does not specify an Internet standard of any kind. Discussion and suggestions for improvement are requested. Distribution of this memo is unlimited. Abstract CBT is a multicast routing architecture that builds a single delivery tree per group...

Microstructures of Tl 2 Ba 2 CuO 6 (Tl-2201) thin ®lms with di€erent doping levels grown on SrTiO 3 substrates were studied by transmission electron microscopy. It is found that Tl-2201 ®lms are epitaxial single phase over large area. A new three-dimensional modulation structure was observed for the heavily overdoped ®lms. With decrease of doping level from heavily overdoped to optimally doped,...

We have searched for HI 21cm absorption toward the two brightest radio AGN at high redshift, J0924–2201 at z = 5.20, and J0913+5919 at z = 5.11, using the Giant Meter Wave Radio Telescope (GMRT). These data set a 3σ upper limit to absorption of < 30% at 40 km s resolution for the 30 mJy source J0913+5919, and < 3% for the 0.55 Jy source J0924–2201 at 20 km s resolution. For J0924–2201, limits t...

232 words Main text (including appendix): 2201 words Figure captions: 307 words Figures: 4 Tables: 0 References: 16

A simple model of anisotropic scattering in a quasi two-dimensional metal is studied. Its simplicity allows an analytic calculation of transport properties using the Boltzmann equation and relaxation time approximation. We argue that the c-axis magnetoresistance provides the key test of this model of transport. We compare this model with experiments on overdoped Tl-2201 and find reasonable agre...

We investigated the effects of Fe substitution on ferromagnetic fluctuations in superconducting overdoped and non-superconducting heavily regimes Bi-2201 cuprates by magnetization electrical resistivity measurements. It was found that spin-glass state induced at low temperatures substitution. The Curie constant effective Bohr magneton, estimated from magnetic susceptibility, as well dimensional...