Aminopyrazolo1, 5-apyrimidines 13 and not the regioisomeric compounds 14.Structures of pyrazolo1, 5-apyrimidines, imidazo1, 2apyrimidines, and pyrimido1, 2-abenzimidazoles, a c, respectively. Helvetica Chimica Acta Vol.triazolo1, 5-c pyrimidine moiety were reported to exhibit remarkable. Also, the tricyclic heterocyclic pyrazolo1, 5-c-1, 2, 4-triazolo4, 3-epyrimidines 2. nzic.org.nzChemProcesse...

New developments are presented in the framework of the model introduced bythe authors in References [1, 2] and in which nucleotides as well ascodons are classified in crystal bases of the quantum group U(q)(sl(2) ⊕ sl (2)) in the limit q → 0. An operator whichgives the correspondence between the amino-acids and the codons isobtained for any known genetic code. The free energy released by basepa...

Deinococcus radiodurans is able to resist and survive extreme DNA damage induced by ionizing radiation and many other DNA-damaging agents. It is believed that it possesses highly efficient DNA repair mechanisms. To characterize the repair pathway of oxidized purines in this bacteria, we have purified, from crude extracts, proteins that recognize these oxidized bases. We report here that D. radi...

The aim of the work was to establish spect­rum biological activity new derivatives 9-bromo-1,2,3,4-tetrahydroacridine due limi­ted amount literature data. In silico prediction selected bromo-derivatives hydrogenated acridines performed using SuperPred 3.0 web resource. obtained results were compared with active drugs that contain acridine cycle in their structure - Tacrine, Amiridine and Amsacr...

Previously we reported that 19 of 42 viruses that infect Chlorella strain NC64A (NC64A viruses) contain a short, nuclear-located, spliceosomal-processed intron in a pyrimidine dimer-specific glycosylase/apyrimidine lyase (pdg) gene. Surprisingly, the nucleotide sequence of the intron region is more conserved than the exon regions of the gene (L. Sun et al., 2000, J. Mol. Evol. 50, 82-92). For c...

Direct observation of enzymes interacting with DNA should be one of the ultimate technologies for investigating the mechanical behavior of the enzymes during the reactions. Atomic force microscopy (AFM) enables observation of biomolecules at a nanoscale spatial resolution; however, for a stable analysis, a scaffold to observe the reaction should be explored. DNA origami has recently been develo...

we give the concept of ‘braiding’ for 2-groupoids, and we show that this structure is equivalent tobraided regular, crossed modules.

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