reaction of tryptamine 1 with dimethyl -3-methoxyallylidenemalonate 2 afforded n?-[4,4-bis (methoxycarbonyl)-1,3-butadienyl] tryptamine 3 which in combination with acetylchloride and pyridine in dichloromethane gave n?, n?-[acetyl]-[(4,4-dinethoxycarbonyl) 1,3butadienyl] tryptamine 4. treatment of 3 with sodium hydroxide afforded 2h[n-(3-indolyl) ethyl] 2-oxo-3-methoxycarbonyl-1-pyridine 5. cyc...

Reaction of tryptamine 1 with dimethyl -3-methoxyallylidenemalonate 2 afforded N?-[4,4-bis (methoxycarbonyl)-1,3-butadienyl] tryptamine 3 which in combination with acetylchloride and pyridine in dichloromethane gave N?, N?-[acetyl]-[(4,4-dinethoxycarbonyl) 1,3butadienyl] tryptamine 4. Treatment of 3 with sodium hydroxide afforded 2H[N-(3-indolyl) ethyl] 2-oxo-3-methoxycarbonyl-1-pyridine 5. Cy...

In the title compound, C(14)H(10)ClNO(2), the dihedral angle between the two rings is 59.4 (2)°. The two carbonyl groups are oriented almost anti-periplanar to each other, with a torsion angle of -160.43 (2)°. In the crystal, mol-ecules are linked into inversion dimers by pairs of N-H⋯O hydrogen bonds.

The infectious diseases caused by antimicrobials pathogens are difficult, harmful, and sometimes impossible to treat. Therefore, design new drugs treat antimicrobial infections is the biggest challenge for modern medicine. 2-Thioxo-4-imidazolidinone used synthesis of a wide variety substituted imidazolidinone derivatives. In this study, we designing eight novel compounds derived 2-thioxo-4-imid...

In the title compound, C(14)H(17)NO(2), the two carbonyl groups are oriented with respect to each other with a torsion angle of -129.9 (3)°. The cyclo-hexane ring adopts a chair conformation. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds into a chain running along the a axis.