Biochemistry Research Division, Department of Cancer Biology, Chief Department of Surgical Oncology (Speciality Clinic) & Director, The Gujarat Cancer & Research Institute, 3 Department of Oral Diagnosis and Dental Radiology, Government Dental College and Hospital Correspondence to: Dr. Prabhudas S. Patel, In-charge, Biochemistry Research Division, The Gujarat Cancer & Research Institute, Asarw...

Building on gene–environment interaction (G E) research, this study examines how the dopamine D4 receptor (DRD4) gene interacts with a situational prime of religion to influence prosocial behavior. Some DRD4 variants tend to be more susceptible to environmental influences, whereas other variants are less susceptible. Thus, certain life environments may be associated with acts of prosociality fo...

Compelling evidence exists for the cardioprotective benefits resulting from consumption of fatty acids from fish oils, EPA (20:5n-3) and DHA (22:6n-3). EPA and DHA alter membrane fluidity, interact with transcription factors such as PPAR and sterol regulatory element binding protein, and are substrates for enzymes including cyclooxygenase, lipoxygenase and cytochrome P450. As a result, fish oil...

Any compensation mechanism that is intended to reward superior investment performance can be gamed by managers who have no superior information or predictive ability; moreover they can capture a sizable amount of the fees intended for the superior managers. We derive precise bounds on the size of this coat‐tail effect and show that it remains substantial even when payments are postponed, bonuse...

What are the equilibrium features of a dynamic …nancial market in which traders care about their reputation for ability? We modify a standard sequential trading model to include traders with career concerns. We show that this market cannot be informationally e¢ cient: there is no equilibrium in which prices converge to the true value, even after an in…nite sequence of trades. We characterize th...

Cryo-electron microscopy can provide high-resolution structural information about cells and organelles in the nearly native, frozen-hydrated state. Applicability, however, is limited by difficulties encountered in preparing suitably thin, vitreously frozen biological specimens. We demonstrate, by cryo-electron tomography of Escherichia coli cells, that a focused ion beam (FIB) can be used to th...

Stomach cancer, the second most common cancer in the world, represents a very important health problem with about 900,000 new cases diagnosed every year, and is a major cause of mortality in Chennai, India. Despite advances in diagnosis and treatment, the 5-year survival rate of stomach cancer is only 25 per cent (Terry et al, 2002). The aetiology of stomach cancer is multifactorial and predomi...