Introduction: Recent research has reported the cytotoxic potential of hydrazones against various strains cancer cells. Aim: To evaluate anticancer activity in vitro and pharmacokinetic profile six synthesized hydrazonic compounds, identified as vanillin 1-phthalazinylhydrazone (VAN-1); 2,4-dinitrophenylhydrazone (VAN-2); phenylhydrazone cinnamaldehyde (CIN-1); isonicotinoyl hydrazone (CIN-2); 1...

Although considerable attention has been given to the identification of keto acids produced during the fermentation of glucose by Escherichia coli, relatively little information has been obtained on the production of aldehydes and ketones. During an investigation of the keto acids produced during glucose fermentation by E. coli 82/r and P6 (D. W. Thayer and J. E. Ogg, Bacteriol. Proc., p. 96, 1...