نتایج جستجو برای: 18-β-glycyrrhetinic acid

تعداد نتایج: 1226919  

2013
Li Wang Douglas H. Sweet

Active components of complementary/alternative medicines and natural supplements are often anionic compounds and flavonoids. As such, organic anion transporters (OATs) may play a key role in their pharmacokinetic and pharmacological profiles, and represent sites for adverse drug-drug interactions. Therefore, we assessed the inhibitory effects of nine natural products, including flavonoids (cate...

Journal: :research in pharmaceutical sciences 0
s. esmaeili f. naghibi m. mosaddegh

with the tremendous expansion in the use of herbal medicine worldwide, safety and efficacy as well as quality control of herbal medicine have become important concerns for both health authority and public. in this paper, the analysis of two st. john's wort (hypericum perforatum) products and four liquorice (glycyrrhiza glabra) products by spectrophotometric and hplc methods, is explained. moreo...

AbstractThe aim of the present study was to formulate poly (lactide-co-glycolide) (PLGA) nanoparticles loaded with 18-β-glycyrrhetinic acid (GLA) with appropriate physicochemical properties and antimicrobial activity. GLA loaded PLGA nanoparticles were prepared with different drug to polymer ratios, acetone contents and sonication times and the antibacterial activity of the developed nanopartic...

AbstractThe aim of the present study was to formulate poly (lactide-co-glycolide) (PLGA) nanoparticles loaded with 18-β-glycyrrhetinic acid (GLA) with appropriate physicochemical properties and antimicrobial activity. GLA loaded PLGA nanoparticles were prepared with different drug to polymer ratios, acetone contents and sonication times and the antibacterial activity of the developed nanopartic...

Journal: :iranian journal of pharmaceutical research 0
behrad darvishi department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran 1417614411, iran saeed manoochehri department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran 1417614411, iran golnaz kamalinia department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences nasrin samadi drug and food control department, faculty of pharmacy, tehran university of medical sciences, tehran1417614411, iran mohsen amini department of medicinal chemistry, faculty of pharmacy, tehran university of medical sciences, tehran1417614411, iran seyyed hossein mostafavi nanotechnology research centre, faculty of pharmacy, tehran university of medical sciences, tehran1417614411, iran

abstractthe aim of the present study was to formulate poly (lactide-co-glycolide) (plga) nanoparticles loaded with 18-β-glycyrrhetinic acid (gla) with appropriate physicochemical properties and antimicrobial activity. gla loaded plga nanoparticles were prepared with different drug to polymer ratios, acetone contents and sonication times and the antibacterial activity of the developed nanopartic...

Journal: :Biological & pharmaceutical bulletin 2013
Hiroaki Hayashi Isao Fujii Munekazu Iinuma Makio Shibano Kazuo Ozaki Hitoshi Watanabe

A triterpene saponin, glucoglycyrrhizin, was isolated from a glycyrrhizin-deficient strain 83-555 of Glycyrrhiza uralensis (Leguminosae), and the structure was determined by chemical and spectral data to be 3-O-[β-D-glucopyranosyl-(1→2)-β-D-glucuronopyranosyl]-glycyrrhetinic acid. Since this saponin has a 2'-O-β-D-glucopyranosyl moiety instead of the 2'-O-β-D-glucuronopyranosyl moiety of glycyr...

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