The development of the vertebrate brain requires an exquisite balance between proliferation and differentiation of neural progenitors. Notch signaling plays a pivotal role in regulating this balance, yet the interaction between signaling and receiving cells remains poorly understood. We have found that numerous nascent neurons and/or intermediate neurogenic progenitors expressing the ligand of ...

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Penelitian ini bertujuan merekonstruksi hubungan perdagangan antar Banten dan Manila tahun 1663-1682 dengan menjawab tiga pertanyaan riset: (1) Bagaimana menjalin dagang Manila, (2) memelihara tersebut dari kontrol VOC, (3) berakhir akibat peperangan Kompeni Belanda. . Metode penelitian yang digunakan adalah metode sejarah, meliputi empat tahap: heuristik, kritik, interpretasi historiografi. Su...

John Fryer, m.d. (Cantab.), f.r.s., may be rightly described as the most observant and learned of all the physicians and surgeons of the East India Company in the 17th century. He came out to India in 1673 and served at various settlements in this country and Persia till 1682. During his journey to his station, Surat, he visited Fort St. George and Masulipatam on the Coromandel coast, and Goa a...