We hypothesized that gene expression profiling may discriminate vanadium from zinc in human bronchial epithelial cells (HBECs). RNA from HBECs exposed to vehicle, V (50 microM), or Zn (50 microM) for 4 hr (n = 4 paired experiments) was hybridized to Affymetrix Hu133A chips. Using one-class t-test with p < 0.01, we identified 140 and 76 genes with treatment:control ratios > or = 2.0 or < or = 0....

BACKGROUND AND AIM This study was planned to evaluate the relationships between the levels of total antioxidant capacity (TAC) and Coenzyme Q (CoQ10) and clinical outcome in hospitalized children with pandemic influenza (H1N1). Serum copper (Cu) and zinc (Zn) levels were also determined to evaluate the changings of oxidative stress's enzyme activities depending on their cofactor concentrations....

Patients who use insulin or oral hypoglycemic medications are at the greatest risk for hypoglycemia. These patients experience mild, self-treated hypoglycemic episodes about twice per week. Severe hypoglycemia, which requires the assistance of another person to regain euglycemia, is experienced at least once per year by 27% of patients treated with intensive insulin regimens. Hypoglycemia is th...

the effect of ca, zn and b foliar application (five g l-1) and their mixed applications as well as two harvest dates (1st and 15st of august) on ppo activity of two commercial asian pears (‘ks’9 and ‘ks’13) fruits at the time of harvest and during storage were investigated. results showed that the ppo activity increased from harvest time to three months after storage and then decreased. during ...

Cysteine cathepsins are defined as lysosomal enzymes that members of the papain family. (Cts) prevalently exist in whole organisms, varying from prokaryotes to mammals, and possess greatly conserved cysteine residues their active sites. Cts engaged digestion cellular proteins, activation zymogens, remodeling extracellular matrix (ECM). Host cells entered by SARS-CoV-2 via endocytosis. Cathepsin...

This study was carried out between May and October, 2010 to morphologically identify Anopheles species in parts of Kano State. A total of 2374 Anopheles were collected and identified. 1782 (75.07%) were collected from Nassarawa Local Government Area while 592 (24.93%) were collected from Tarauni Local Government Area. Using Anopheles characters of Gilles and Coetzee (1987) under zeiss light mic...

During the process of drug discovery, the pharmaceutical industry is faced with numerous challenges. One challenge is the successful prediction of the major routes of human clearance of new medications. For compounds cleared by metabolism, accurate predictions help provide an early risk assessment of their potential to exhibit significant interpatient differences in pharmacokinetics via routes ...