The inward Na+ current underlying the action potential in nerve is terminated by inactivation. The preceding report shows that deletions within the intracellular linker between domains III and IV remove inactivation, but mutation of conserved basic and paired acidic amino acids has little effect. Here we show that substitution of glutamine for three clustered hydrophobic amino acids, Ile-1488, ...

E-cadherin is a trans-membrane tumor suppressor responsible for epithelial cell adhesion. E-cadherin forms adhesive clusters through combined extra-cellular cisand trans-interactions and intracellular interaction with the actin cytoskeleton. Here we identify four populations of E-cadherin within cell junctions based on the molecular interactions which determine their mobility and adhesive prope...

Author(s) Chandra, Anjan Kumar; Inoue, Jun-ichi Citation International Journal of Modern Physics C, 21(12): 1489-1500 Issue Date 2010-12 Doc URL http://hdl.handle.net/2115/44582 Right Electronic version of an article published as International Journal of Modern Physics C, Volume 21, Issue 12, 2010, 1489-1500, 10.1142/S0129183110015993 © copyright World Scientific Publishing Company, http://www....

Karin Nylén, Ludwig Z. Csajbok, Martin Öst, Anas Rashid, Kaj Blennow, Bengt Nellgård and Aneurysmal Subarachnoid Hemorrhage Serum Glial Fibrillary Acidic Protein Is Related to Focal Brain Injury and Outcome After Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2007 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Ave...

The purpose of this presentation is to outline the Museum Multimedia (MM) experience in Russia. I am quite not sure wether all my colleagues experts and museum community in West Europe and America are intimately familiar with Russian experience in this sphere and I am pleased to have this opportunity to fill the gap. I will mainly focus on the general picture for some more reports with detailed...

, 1489 (2014); 344 Science et al. K. F. Mak transistors 2 The valley Hall effect in MoS This copy is for your personal, non-commercial use only. clicking here. colleagues, clients, or customers by , you can order high-quality copies for your If you wish to distribute this article to others here. following the guidelines can be obtained by Permission to republish or repurpose articles or portio...

Combined QM/MM calculations of an activesite of Cytochrome P450cam have been performed, before and after a binding process of Cytochrome P450cam to Putidaredoxin. The calculations have been carried out for two coordination spheres of the heme active-site of Cytochrome P450cam, namely a 5-coordinated, and a 6coordinated system of this protein having a water molecule as a 6th ligand. An experimen...