Whole-brain voxel-based unbiased resting state functional connectivity was analysed in 418 subjects with autism and 509 matched typically developing individuals. We identified a key system in the middle temporal gyrus/superior temporal sulcus region that has reduced cortical functional connectivity (and increased with the medial thalamus), which is implicated in face expression processing invol...

A. The endogenous opioid system and natural reinforcement 1383 B. The endogenous opioid system and drugs of abuse 1387 C. Perspectives: extending studies to animal models of drug addiction 1393 IV. Genetic Manipulation of the Opioid System, Reinforcement, and Drug Dependence 1393 A. Opioid receptor knockout mice 1393 B. Opioid peptide knockout mice 1394 C. Conclusion 1395 D. Perspectives: towar...

The chronic effects of glycine transporter 1 and 2 inhibitors (sarcosine and ALX-1393, respectively) on miniature inhibitory postsynaptic currents were studied in cultured spinal neurons. We found that sarcosine increased the frequency of overall miniature inhibitory postsynaptic currents without affecting the ratio of glycinergic, mixed and GABAergic miniature inhibitory postsynaptic currents,...

Stem borer (SB) and more recently, fall armyworm (FAW) are serious economic pests in maize production sub-Saharan Africa. It is hypothesized that SB-resistant germplasm may confer resistance against FAW. However, the performance of lines hybrid combinations inheritance FAW-resistant traits under variable FAW infestations have not been reported. This study was conducted to (i) obtain information...

In this paper we seek to identify those childhood interventions that show real promise of positively influencing children's human capital accumulation. Next we explore the quality of existing research on these interventions; establish a set of quality standards that can be applied to evaluations of childhood interventions and finally focus on the extent to which research can link the interventi...

This article illuminates the transmedia storytelling techniques in The Walking Dead comic book and video game. Telltale Games’ The Walking Dead localizes itself within the comic book world of The Walking Dead by acting as a transmedia storytelling device and using intertextuality comics to assist game players with meaning-making. By participating in the game, Telltale rewards players with addit...

BACKGROUND Infection with high-risk human papillomavirus (HPV)types has been recognized as a causal factor for the development of cervical cancer and a number of other malignancies. Today, vaccines against HPV, highly effective in the prevention of persistent infection and precancerous lesions, are available for the routine clinical practice. OBJECTIVES The data on the prevalence and type-spe...

Representations of femininity in video games and other media are often discussed with reference to the most popular games, their protagonists and their sexist predicament. This framing leaves in shadow other dimensions. We aim to identify some of them and to open a broader horizon for examining and designing femininity and gender in games. To this end we look into games with creative portrayals...