This study investigates acoustic correlates of the putative breathy and clear phonation type contrast in a dialect of Khmer (Cambodian) spoken in Chanthaburi Province, Thailand. The goal is to determine whether this Khmer dialect still preserves this historical contrast. Out of seven acoustic parameters measured, four, namely H1 H2; H1 A1; H1 A3; and vowel RMS amplitude successfully distinguish...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 185 No. 7 1227–1242 www.jcb.org/cgi/doi/10.1083/jcb.200811081 JCB 1227 F. Fröhlich and K. Moreira contributed equally to this paper. Correspondence to Tobias C. Walther: [email protected] Abbreviations used in this paper: LC, liquid chromatography; MCC, membrane compartment occupied by Can1; MCP, membrane compartment occupied by P...

This study tested the activity of LD-1227, which contains a caviar-derived homogenate added with coenzyme Q(10) (CoQ(10))-selenium component (CaviarLieri(®), Lab-Dom, Switzerland), in aged human skin and its potential role on skin mitochondria function. Human dermal fibroblasts were obtained from healthy donors over 70 years old and treated with LD-1227 for 72 hr. As compared to baseline, LD-12...

Renal fibrosis is a serious clinical problem resulting in the greatest need for renal replacement therapy. No adequate preventive or curative therapy is available that could be clinically used to target renal fibrosis specifically. The search for new efficacious treatment strategies is therefore warranted. Although in vitro models using homogeneous cell populations have contributed to the under...

Unsafe use of alcohol results in approximately 2.5 million deaths worldwide, with cirrhosis contributing to 16.6% of reported deaths. Serum insulin levels are often elevated in alcoholism and may result in diabetes, which is why alcoholic liver disease and diabetes often are present together. Because there is a sizable population with these diseases alone or in combination, the purpose of this ...

The in vitro antibacterial activity of AM-1155 against a wide variety of clinical isolates was compared with those of other fluoroquinolones. The MICs of AM-1155 for 90% of Staphylococcus aureus, Streptococcus pneumoniae, and Enterococcus faecalis isolates tested were 0.10, 0.39, and 0.78 microgram/ml, respectively. The antibacterial activity of AM-1155 against gram-positive bacteria and anaero...

Background:  We aimed to report outcomes of total hip arthroplasty (THA) in very young patients under the year of 30.   Methods:  Thirty patients (45 hips) with various indications for THA were retrospectively reviewed radiologically and clinically and analyzed regarding survival, reasons of failure, factors associated with outcomes and postoperative complications.   Results:  Within a mean fol...

Background and Aims: Total hip arthroplasty (THA) is a common orthopedic surgery. The main focus in the research of THA is immune responses in these patients following the blood transfusion.Therefore, in this study, we evaluated the immune modulation indexes such as T cell amplification, Tcell surface markers and also production of cytokines in the patients undergoing THA surgery following bloo...

Community health workers (CHWs) are increasingly recognized as an integral component of the health workforce needed to achieve public health goals in lowand middle-income countries (LMICs). Many factors influence CHW performance. A systematic review was conducted to identify intervention design related factors influencing performance of CHWs. We systematically searched six databases for quantit...