A mathematical model is presented for the spread of viral diseases within human or other populations in which both the dynamics of viral growth within individuals and the interactions between individuals are taken into account. We thus bridge the classical macroscopic approach to the growth and population dynamics of disease at the microscopic level. Each member, i , of the population of n indi...

OBJECTIVE As one of potential candidate genes for the risk of Parkinson's disease (PD), the HLA-DRA/PARK18 (rs3129882, A > G) gene has been studied extensively. However, direct evidence for the genetic association studies between PD and rs3129882 remains inconclusive. The aim of our meta-analysis was to determine a more reliable association between the rs3129882 and PD. MATERIALS AND METHODS ...

OBJECTIVE To investigate the association of hyperglycemia with blood pressure control goal in the patients with type 2 diabetes (T2D) cared by tertiary hospitals in China. STUDY DESIGN AND METHODS A cross sectional survey of 29442 patients was conducted in 77 tertiary hospitals in 4 major cities in China in 2011 and 18350 of them without known hypertension were used in the analysis. Univariab...

The genome of trypanosomatids rearranges by using repeated sequences as platforms for amplification or deletion genomic segments. These stochastic recombination events have a direct impact on gene dosage and foster the selection adaptive traits in response to environmental pressure. We provide here such an example showing that phosphoenolpyruvate carboxykinase (PEPCK) knockout (?pepck) leads ev...

•A high-throughput experimental approach is reported to synthesize materials•The emissions are controlled by tuning the concentration and oxidation state of dopants•Machine learning used predict conditions for designing white phosphors White drawing attention their potential use in next generation LEDs, which significantly reducing energy consumption lighting. Doping multiple activators one hos...