Loss of neurons that express the neuropeptide hypocretin (Hcrt) has been implicated in narcolepsy, a debilitating disorder characterized by excessive daytime sleepiness and cataplexy. Cell replacement therapy, using Hcrt-expressing neurons generated in vitro, is a potentially useful therapeutic approach, but factors sufficient to specify Hcrt neurons are unknown. Using zebrafish as a highthroug...

An underlying assumption of the above parametric approach is that the process is a = Gaussian field, i.e., its statistical characteristics, including its roughness parameter (or its reciprocal, the smoothness ) ), are the same at each point in the image. The FWHM of the process should be constant in all directions and across all voxels in the image. While these assumptions are reasonable for fu...

Institute for Optical Materials and Technologies “Acad. J. Malinowski”, Bulgarian Academy of Sciences, “Acad. G. Bonchev” str. Bl. 109, 1113 Sofia, Bulgaria Sofia University.”St. Kliment Ohridski, Faculty of Chemistry and Farmacy, 1 James Bourchier Blvd., 1164 Sofia, Bulgaria Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, “Acad. G. Bonchev” str. Bl....

The historical sediment record of Lake Sonachi (Kenya) was used to study the influence of lake depth and mixing regime on patterns of sedimentation in a small, fluctuating tropical soda lake. Lake Sonachi last desiccated completely in the early nineteenth century and has fluctuated between 3and 18-m lake depth over the past 115 yr. A freeze-core of offshore sediments describes recent lake histo...

Journal of the Operational Research Society, 58, No. 8 (2007), pp. 1109-1113. Personal, noncommercial use permitted on the condition that proper reference is given to the following publication: Ulrich, W. (2007). Philosophy for professionals: towards critical pragmatism. Viewpoint, Journal of the Operational Research Society, 58, No. 8, pp. 1109-1113. [ISSN 0160-5682] [HTML] http://www.palgrave...

María Clavin1, Silvia Cazorla2,3, Renata Spina4, Miguel A. Sosa4, Emilio Malchiodi2, Virginia Martino1, Fernanda Frank2,3,†, Liliana Muschietti1,†,* 1Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Farmacognosia. IQUIMEFA (UBACONICET), Junín 956 2° F (1113), Buenos Aires, Argentina. 2Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Inmunologí...

M.F. Desimone a,1, M.C. De Marzi b,1, G.J. Copello a, M.M. Fernández b, F.L. Pieckenstain c, E.L. Malchiodi b, L.E. Diaz a,∗ a Cátedra de Quı́mica Analı́tica Instrumental, Facultad de Farmacia y Bioquı́mica, Universidad de Buenos Aires, Junı́n 956 Piso 3◦ (1113) Ciudad de Buenos Aires, Argentina b Cátedra de Inmunologı́a, IDEHU-CONICET, Facultad de Farmacia y Bioquı́mica, Universidad de Buenos Aires,...