In the centrosymmetric dinuclear title complex, [Mn(2)(C(16)H(10)NO(2))(4)(C(12)H(8)N(2))(2)(H(2)O)(2)]·2H(2)O, the Mn(II) cation is in a distorted octa-hedral coordination geometry defined by two N atoms from a 1,10-phenanthroline ligand, one water O atom and three O atoms from three 2-phenyl-quinoline-4-carboxyl-ate anions. A pair of 2-phenyl-quinoline-4-carboxyl-ate anions bridge two Mn cati...

The induction of benoxaprofen (BNX) glucuronidation in rats by intragastric administration of three nitrogen heterocycles (quinoline, 2,2'-dipyridyl, or 1,7-phenanthroline at 75 mg/kg daily for 3 days) has been investigated. BNX was administered i.v. at a dose of 20 mg/kg to bile-cannulated rats that had been induced. Blood and bile were collected over 8 h. Liver tissues were also collected at ...

In the last decade, progress has been made in G-quadruplex (G4) ligands development, but for most compounds, ligand binding mode is speculative or based on low resolution methods, with its discovery structure-based approaches. Herein, we report synthesis of small (MW < 400 Da) heterocycle containing different aromatic scaffolds, such as phenyl, quinoline, naphthalene, phenanthroline and acri...

Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor through which dioxins and carcinogenic polycyclic aromatic hydrocarbons cause altered gene expression and toxicity. Ten aza-polycyclic aromatic hydrocarbons (aza-PAHs), consisting of nitrogen substituted naphthalenes, phenanthrenes, chrysenes, and benzo[a]pyrenes (BaPs), were subjected to analysis of their structure-acti...

Recombination zone and Förster resonance energy transfer (FRET) in multilayer organic light-emitting diodes (OLEDs) were investigated. Basis device architecture is indium tin oxide (ITO)/N, N0-diphenyl-N, N0-bis(1-naphthyl-phenyl)-1, 10-biphenyl-4, 40-diamine (NPB)/4-(dicyanomethylene)-2-tert-butyl-6-(1, 1, 7, 7tetramethyljulolidyl-9-enyl)-4H-pyran (DCJTB)/NPB (spacer)/tris-(8-hydroxyl quinolin...

Caenorhabditis elegans is a free-living soil nematode that is commonly used as a model for toxicity tests. The aim of this study was to investigate the toxicity of seven organic pollutants: four azaarenes (quinoline, acridine, phenazine, and 1,10-phenanthroline), short-chain chlorinated paraffins, and two organochlorinated pesticides (toxaphene and hexachlorobenzene). The exposure to all chemic...