In this study, we examined the role of 5-hydroxytryptamine (5-HT)1A and alpha1-adrenergic receptors in the hypothermia induced by 1-(2-methoxyphenyl)-4-[4-(2-phthalimido)butyl]-piperazine (NAN-190) and its analogs, 1-(2-methoxyphenyl)-4-[(4-succinimido)butyl]piperazine (MM77) and trans-1(2-methoxyphenyl)-4-[4-(2-phthalimido)cyclohexyl]piperazine (MP245), which--like NAN-190--showed a high affin...

Volume 29, Number 4, July/August 1997 language would, in practice, have serious unintended consequences, such as nullifying laws allowing minors to obtain confidential reproductive health care and other sensitive health services, disrupting school sex education and AIDS prevention activities, and impeding the removal of children from abusive homes. However, the outcome also appears to reflect a...

Hyperkalemia is an electrolyte abnormality that may cause cardiac pacemaker malfunction. Clinically, bilateral calf pain is extremely rare in hyperkalemia. Here we presented a case of a 78-year-old female who had bilateral calf pain with electrocardiographic changes in severe hyperkalemia.

Seventy years have elapsed since the Nutrition Society was founded and John Boyd Orr became its first Chairman. Over the intervening period, nutrition research has embraced and responded to a wide variety of challenges as the requirements of research have evolved and changed. This paper reflects on some of the major challenges that have influenced nutrition research over the past 70 years and c...

Childhood obesity is an issue of public health concern globally. This review reports on levels of overweight and obesity in Irish children and examines some aspects of their diet and lifestyle proposed to promote or protect against increasing body fatness in children. While there is still some debate with regard to the most appropriate cut-off points to use when assessing body fatness in childr...

consequences of unprotected intercourse or contraceptive failure: It is estimated that among Australian teenagers, one abortion occurs for every teenage birth,7 and that the number of teenagers having abortions each year has more than doubled since 1971.8 Young people in Australia are exposed to two potentially conflicting discourses regarding sexual health: one focusing on safer sex and the ot...

Deferasirox is an orally effective iron (Fe) chelator currently used for the treatment of iron-overload disease and has been implemented as an alternative to the gold standard chelator, desferrioxamine (DFO). Earlier studies demonstrated that DFO exhibits anticancer activity due to its ability to deplete cancer cells of iron. In this investigation, we examined the in vitro and in vivo activity ...

The dataset to be analyzed is the dataset of Reddit submissions suggested in lecture. (http://snap.stanford.edu/data/webReddit.html). In this dataset, there are 132,308 entries for analysis. Of these entries, however, there are only 16,736 unique images, and on average, each was resubmitted approximately 7.9 times. The timespan across which these Reddit submissions were made is July 2008 to Jan...